Figure 3
Comparison of the E. histolytica genes modulated upon L-cysteine deprivation and oxidative or nitrosative stress. A) Expression kinetics upon L-cysteine deprivation of the genes previously inferred for oxidative and/or nitrosative stress defense. Gene/protein ID of enzymes are: type A flavoproteins (Flavodiiron proteins), EHI_159860, EHI_064530, EHI_096710, and EHI_129890; peroxiredoxin, EHI_145840; iron containing SOD, EHI_159160; rubrerythrin, EHI_134810; hybrid cluster protein, EHI_004600. B ) A Venn diagram showing the number of overlapping genes modulated upon L-cysteine deprivation and oxidative (1 mM of H2O2 for 1 h), or nitrosative stress (200 μM of DPTA-NONOate for 1 h), as described [23].