Figure 7

Example of a reciprocal breakpoint pair. Schematic example of a reciprocal breakpoint pair. In this schematic representation of two parts of the mouse and human genomes (blue rectangles represent synteny blocks), a simple rearrangement is represented: the inversion of the synteny block B. Following the definition of breakpoint pairs, looking at the mouse breakpoint (A _m - B _m ), the two human breakpoints (A _h - B _h ) and (B _h - C _h ) are grouped together (in red). Then, looking at the mouse breakpoint (B _m - C _m ), we can also group together the two human breakpoints (A _h - B _h ) and (B _h - C _h ) (in green). Thus these two human breakpoints cannot be grouped with any other breakpoint and are referred to as a reciprocal breakpoint pair.