Figure 7

Alignment of salmonid and mammalian SOX9 high mobility group (HMG) domains. The mammalian and salmonid bipartite nuclear localization signal (NLS-1) and basic cluster NLS (NLS-2) are found in positions at the N- and C-termini of the HMG domain, respectively. The nuclear export signal (NES) is centrally located between the two NLSs. The C-terminal protein interface and transactivation domain residues are not shown.