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Figure 3 | BMC Genomics

Figure 3

From: Chromosome-wide mapping of DNA methylation patterns in normal and malignant prostate cells reveals pervasive methylation of gene-associated and conserved intergenic sequences

Figure 3

Methylation of 3' downstream regions. A, Methylated regions in LNCaP (left) and hypermethylated regions in LNCaP (right) are enriched for sequences within 2 kbp downstream of gene transcriptional termination sites. Conventions are the same as for Fig. 2A. B, DNA methylation signals at a representative 3' downstream gene hypermethylated region in LNCaP cells compared to the PrEC cells. Conventions are the same as for Figure. 2B. C, Bisulfite verification of a hypermethyalted region (boxed region from panel (B)) downstream of the DSCR9 and DSCR3 genes. Conventions are the same as for Figure. 2C.

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BMC Genomics

ISSN: 1471-2164

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