Skip to main content
Figure 2 | BMC Genomics

Figure 2

From: Global analysis of estrogen receptor beta binding to breast cancer cell genome reveals an extensive interplay with estrogen receptor alpha for target gene regulation

Figure 2

Gene expression differences in absence or presence of ERβ. Top: Heatmap summarizing the effects of ERβ expression of the estrogen responsive transcriptome of MCF-7 cells, showing changes in expression (log2 of the fold-change) of 921 transcripts after cell exposure to 10-8M E2 for the indicated times. Transcripts are grouped as follows: regulated only in wt MCF-7 cells (1), in both cell lines (2) and only in TAP-ERβ cells (3). Bottom: Venn diagram showing the numbers of differentially regulated by E2 in wt MCF-7 only (1), both cell lines (2) or ERβ expressing cells only (3).

Back to article page
\