Comparative analysis of two complete Corynebacterium ulcerans genomes and detection of candidate virulence factors

Table 5 Overview of candidate virulence factors detected in the C. ulcerans genomes

ID in 809	ID in BR-AD22	Gene	Proposed function of deduced protein	LP×TG^a
CULC809_00177	-	rbp	Ribosome-binding protein	none
CULC809_01974	CULC22_02125	cpp ^b	Corynebacterial protease CP40^b	none
CULC809_00040	CULC22_00038	pld	Phospholipase D	none
CULC809_01949	CULC22_02103	spaF	Surface-anchored protein (pilus subunit)	LPKTG
CULC809_01950	CULC22_02104	spaE	Surface-anchored protein (pilus subunit)	LPLTG
CULC809_01952	CULC22_02106	spaD	Surface-anchored protein (pilus subunit)	LPMTG
CULC809_01979	CULC22_02130	spaC	Surface-anchored protein (pilus subunit)	LPLTG
CULC809_01980	CULC22_02131	spaB	Surface-anchored protein (pilus subunit)	LARTG
CULC809_01133	CULC22_01148	rpfI	Rpf interacting protein	none
CULC809_01521	CULC22_01537	cwlH	Cell wall-associated hydrolase	none
CULC809_00434	CULC22_00437	nanH	Sialidase precursor (neuraminidase H)	none
CULC809_00509	CULC22_00515	vsp1	Venome serine protease	none
CULC809_01964	-	vsp2	Venome serine protease	none
CULC809_01848	CULC22_02007	tspA	Trypsin-like serine protease	none

^a Predicted LPxTG motif used for anchoring of the protein to the cell wall
^b Data presented in this manuscript indicates a function as endoglycosidase. The gene should therefore be renamed as ndoE.

ISSN: 1471-2164