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Table 3 Partial coefficient of Grantham distance, GC content, gene density, CpG island density, and chromosome size obtained by multiple regression analysis

From: A codon substitution model that incorporates the effect of the GC contents, the gene density and the density of CpG islands of human chromosomes

Type

Partial Correlation Coefficient ± SD

Intercept

CpG to TpG

5.13 ± 0.40

TpG to CpG

2.59 ± 0.04

non-CpG Transition

3.09 ± 0.17

Transversion

3.84 ± 0.14

Grantham Distance

CpG to TpG

-5.05 × 10-3 ± 2.29 × 10-4**

TpG to CpG

-9.48 × 10-3 ± 2.25 × 104**

non-CpG Transition

-7.81 × 10-3 ± 9.79 × 10-5**

Transversion

-3.91 × 10-3 ± 7.25 × 10-5**

GC Content (%)

CpG to TpG

-7.13 × 10-2 ± 1.03 × 10-2**

TpG to CpG

-1.52 × 10-2 ± 1.01 × 10-2

non-CpG Transition

-3.23 × 10-2 ± 4.40 × 10-3**

Transversion

-6.18 × 10-2 ± 3.66 × 10-3**

Gene Density a

CpG to TpG

7.21 × 10-3 ± 1.68 × 10-3**

TpG to CpG

8.36 × 10-3 ± 1.62 × 10-3**

non-CpG Transition

8.14 × 10-3 ± 6.94 × 10-4**

Transversion

9.78 × 10-3 ± 5.55 × 10-4**

CpG Island Density a

CpG to TpG

-4.23 × 10-2 ± 6.72 × 10-3**

TpG to CpG

-5.38 × 10-2 ± 6.46 × 10-3**

non-CpG Transition

-4.64 × 10-2 ± 2.80 × 10-3**

Transversion

-5.76 × 10-2 ± 2.25 × 10-3**

Chromosome Size

CpG to TpG

-3.83 × 10-9 ± 2.64 × 10-10**

TpG to CpG

-4.70 × 10-9 ± 2.52 × 10-10**

non-CpG Transition

-4.30 × 10-9 ± 1.08 × 10-10**

Transversion

-5.65 × 10-9 -9 ± 8.40 × 10-11 **

  1. *at 1% level of significance; **at 0.1% level of significance; aper Mb