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Table 1 The DE genes associated with immune and inflammatory responses on PID 3

From: Transcription analysis on response of swine lung to H1N1 swine influenza virus

Functional
classification
Gene description Gene symbol Fold Change Gen Bank ID
  CD45 antigen isoform 3 Fragment CD45 38.62459 AK230523
  Sus scrofa antibacterial protein PMAP-23 21.70289 EW419136
  Sus scrofa peptide antibiotic PR39 PR39 13.50724 NM_214450
immune Sus scrofa chemokine ligand 26-like mRNA CCL26 8.645769 NM_001078665
response Sus scrofa protegrin 4 NPG4, mRNA NPG4 8.237142 NM_213863
  Sus scrofa immunoglobulin kappa variable group IGKV 6.440473 CB286369
  Sus scrofa 2'-5'-oligoadenylate synthetase-like mRNA OASL 5.803129 NM_001031790
  Interferon-stimulated gene 20 kDa protein ISG20 5.414398 NM_001005351.2
  Sus scrofa chemokine C-X-C motif ligand 10 mRNA CXCL10 5.329808 NM_001008691
  Rep: IL-1 receptor 2-Bos taurus Bovine, partial 98% IL1R2 5.321422 NM_001046210.1
  Sus scrofa MHC class II histocompatibility antigen SLA-DQA1 5.232868 AK230483
  Sus scrofa cathepsin L1-like CTSL1 4.814094 AK230898
  Sus scrofa interferon regulatory factor 3 (IRF3), mRNA IRF3 4.320395 NM_213770
  Sus scrofa Fc fragment of IgG, low affinity IIb, receptor, mRNA FCGR2B 3.622257 NM_001033013
  Sus scrofa CD14 molecule, mRNA CD14 3.544918 NM_001097445
  Sus scrofa interferon stimulated gene 15 mRNA ISG15 3.45 EU584557.1
  Sus scrofa IgG heavy chain LOC396781, mRNA IgG 3.438582 NM_213828
  Sus scrofa interferon-induced protein with tetratricopeptide repeats 1 IFI56 3.386147 XM_001928724
  Sus scrofa inducible T-cell co-stimulator ICOS, mRNA ICOS 3.353116 NM_001044546
  Sus scrofa interferon regulatory factor 7 IRF7, mRNA IRF7 3.249327 NM_001097428
  Sus scrofa myxovirus influenza virus resistance 1, interferon-inducible protein p78 MX1, mRNA MX1 3.237013 NM_214061
  Sus scrofa MHC class I antigen SLA-2 3.187732 AK231553
  Sus scrofa cytotoxic T-lymphocyte-associated protein 4 CTLA4, mRNA CTLA4 3.184663 NM_214149
  Sus scrofa DEAD Asp-Glu-Ala-Asp box polypeptide 58 DDX58, mRNA DDX58 3.122048 NM_213804
  Rep:Tumor necrosis factor receptor superfamily member 17-Homo sapiens TNFRSF17 3.071191 NM_001192.2
  Sus scrofa CD8a molecule CD8A, mRNA CD8A 2.834259 NM_001001907
  Similar to melanoma cell adhesion molecule CD146 -2.819245 BX915975
  similar to guanylate binding protein 4 GBP4 2.780124 AK239735
  Sus scrofa guanylate binding protein 1, interferon-inducible, 67 kDa GBP1, mRNA GBP1 2.765026 NM_001128473
  Sus scrofa ubiquitin specific peptidase 18, mRNA USP18 2.732302 NM_213826
  Sus scrofa interferon-induced protein with tetratricopeptide repeats 2 mRNA IFI54 2.729199 AK230663
  mast cell immunoreceptor signal transducer-like CLNK 2.704822 AK237804
  Rep:CD274 molecule CD274, mRNA- Homo sapiens CD274 2.648947 EW655654
  Sus scrofa CD163 molecule CD163, mRNA CD163 2.633336 NM_213976
  Sus scrofa interferon-induced protein 44 mRNA IFI44 2.629777 AK233687
  Sus scrofa interleukin 12A natural killer cell stimulatory factor 1, IL12A, mRNA IL12A 2.580563 NM_213993
  Sus scrofa guanylate binding protein 2, interferon-inducible GBP2, mRNA GBP2 2.561492 NM_001128474
  Sus scrofa interferon-induced protein with tetratricopeptide repeats 3, mRNA IFI60 2.465327 XM_001928703
  Sus scrofa interferon-induced transmembrane protein 1 IFITM1 2.407903 AK237820
  Sus scrofa chemokine C-C motif receptor 5, mRNA CCR5 2.374719 NM_001001618
  Sus scrofa chemokine C-C motif receptor 10, mRNA CCR10 2.36215 NM_001044563
  Sus scrofa chemokine C-C motif ligand 28, mRNA CCL28 2.330211 NM_001024695
  Sus scrofa chemokine C-X-C motif ligand 9 mRNA CXCL9 2.312722 BP169836
  Sus scrofa transporter 1, ATP-binding cassette, sub-family B MDR/TAP TAP1, mRNA TAP1 2.15635 NM_001044581
  Sus scrofa Fas ligand TNF superfamily, member 6, mRNA FAS 2.098484 NM_213806
  Sus scrofa immunoglobulin-associated alpha CD79A, mRNA CD79A 2.086904 NM_001135962
  Sus scrofa interferon induced with helicase C domain 1 IFIH1, mRNA IFIH1 2.075703 NM_001100194
  Sus scrofa aquaporin 9, mRNA AQP9 2.067154 NM_001112684
  Sus scrofa tumor necrosis factor superfamily member 18 mRNA, partial cds TNFSF18 2.065184 DQ995649
  Sus scrofa 2'-5'-oligoadenylate synthetase 2, 69/71kDa OAS2, mRNA OAS2 2.054377 NM_001031796
  similar to cystatin F CST7 2.042642 CJ009409
  Sus scrofa Ig gamma 2b chain constant region IGG2B 2.017483 AK237225
  Sus scrofa CD86 molecule CD86, mRNA CD86 2.007655 NM_214222
  Sus scrofa vitronectin VTN, mRNA VTN -2.006228 NM_214104
  Sus scrofa chemokine ligand 26-like protein LOC780409, mRNA CCL26 8.645769 NM_001078665
  Sus scrofa Toll-like receptor 3 TLR3 7.331916 NM_001097444.1
  Sus scrofa chemokine C-X-C motif ligand 10, mRNA CXCL10 5.329808 NM_001008691
  Sus scrofa selectin L (SELL), mRNA SELL 4.497706 NM_001112678
inflammatory Sus scrofa inflammatory response protein 6, mRNA IRG6 3.840661 NM_213817
response Sus scrofa C1q-related factor LOC780424, mRNA CRF 3.627351 NM_001078676
  Sus scrofa CD14 molecule CD14, mRNA CD14 3.544918 NM_001097445
  Sus scrofa alpha-1-antichymotrypsin 2 SERPINA3-2 SERPINA3 3.119463 NM_213787
  Sus scrofa complement C4 C4, mRNA C4 2.949702 NM_001123089
  Sus scrofa selectin E SELE, mRNA SELE -2.879741 NM_214268
  Sus scrofa toll-like receptor 2 (TLR2), mRNA TLR2 2.8723 NM_213761
  Similar to melanoma cell adhesion molecule CD146 -2.819245 BX915975
  Sus scrofa toll-like receptor 8 TLR8, mRNA TLR8 2.675719 NM_214187
  Sus scrofa CD163 molecule CD163, mRNA CD163 2.633336 NM_213976
  Rep: transforming growth factor, beta 2- Macaca mulatta TGFB2 -2.554227 EV858461
  Sus scrofa chemokine C-C motif receptor 5, mRNA CCR5 2.374719 NM_001001618
  Sus scrofa chemokine C-C motif ligand 28, mRNA CCL28 2.330211 NM_001024695
  Sus scrofa chemokine C-X-C motif ligand 9 CXCL9 2.312722 BP169836
  Sus scrofa serpin peptidase inhibitor, clade E member 1 SERPINE1, mRNA SERPINE1 2.225002 NM_213910
  Sus scrofa Toll-like receptor 9 TLR9, mRNA TLR9 2.200666 NM_213958
  Rep: arachidonate 15-lipoxygenase Alox15 gene- Mus musculus Alox15 -2.168114 AK238353
  Sus scrofa signal transducer and activator of transcription 1 STAT1, mRNA STAT1 2.116864 NM_213769
  Sus scrofa S100 calcium binding protein A2 S100A2 2.04835 XM_001929556
  Sus scrofa serpin peptidase inhibitor, clade G1 inhibitor, member 1 SERPING1, mRNA SERPING1 2.022489 NM_001123194
  1. The DE genes associated with immune and inflammatory responses were assigned based on GO term and manual annotation. Manual annotations were listed in italics. Most genes could also be classified into other categories but only immune and inflammatory responses were considered.