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Figure 1 | BMC Genomics

Figure 1

From: Transcriptional responses to glucose in Saccharomyces cerevisiae strains lacking a functional protein kinase A

Figure 1

Relationships between Tpk1, 2, 3, Rim15, Msn2/4 and Yak1. Activated Tpks can phosphorylate Msn2/4 and Rim15 leading to their export to the cytoplasm, thus reducing the transcription rate of YAK1 and allowing growth. In the absence of Tpks, Rim15 and Msn2/4 are not phosphorylated and remain in the nucleus, in an active or potentially active form. Rim15 activates Msn2/4, Msn2/4 activate the transcription of YAK1 and Yak1 blocks cellular growth.

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