Distribution of modified histones around transcription start sites (TSSs). Distributions of nucleosomes containing methylated and acetylated histones. (A) H3K4me1, (B) H3K4me2, and (C) H3K4me3 and (D) H3K9ac around TSSs are shown. All of the modified histones were highly enriched around the TSSs associated with broad promoters, unlike those associated with peak promoters. The x-axis shows the genomic positions with respect to the TSSs (from -5 kb to 5 kb).