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Figure 5 | BMC Genomics

Figure 5

From: Tissue-specific gene expression templates for accurate molecular characterization of the normal physiological states of multiple human tissues with implication in development and cancer studies

Figure 5

The GET from adult lung in our training set positively correlates with development of human embryonic lungs. Correlation between the 56-gene profiles from each of the human fetal lung samples (GSE14334) and that from our adult lung template were computed and plotted. The x-axis indicates age (in "days post conception") of the fetal samples and y-axis the correlation coefficient. As each of the samples in the test data came from different individuals, they may show genetic variation as well as different pathology. The slope of the regression line as displayed to the upper right corner was 0.0016 with P value = 0.00034 on t-test. The regression slopes for correlation with each of the 24 tissues was computed, and was highest with the lung samples. (see Additional file 1: Table S4).

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BMC Genomics

ISSN: 1471-2164

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