Table 2 Transcriptional complexity and discovery across regulators of kidney development

Pax2

NC

-

Alt. 5'/Promoter

-

Signal

Pax2a/b

chr19:44865283-44890407

Cassette Exon

ENSMUST00000111979

13

chr19:44831917-44835374

Donor/Acceptor

Pax2.bSep07

13

NC

chr19:44909958-44910469

Donor/Acceptor

N/A

10

Wt1

NC

chr2:104973652-105003491

Skip exon 4 &5

ENSMUST00000111100

10

Wt1 -exon 5

chr2:104983310-105003491

Skip exon 5

ENSMUST00000111101

350

+/- KTS

chr2:105010157-105012389

Donor/Acceptor

ENSMUST00000139585

83

Sall1

Isoform A (long) & B (short)

chr8:91557288-91566260

Alt. 5'/promoter

A: (hg19)NM_002968

B: (hg19)NM_001127892

9

NC

chr8:91566334-91567384

Overlapping Exon

Sall1.dSep07

5

Eya1

NC

chr1:14294546-14294663

Alt. Exon

Eya1.fSep07

3

Isoform 1-4

chr1:14273270-14294515

Cassette Exon

ENSMUST00000080664

10

chr1:14260914-14264155

Donor/Acceptor

ENSMUST00000027066

32

chr1:14264215-14264624

Donor/Acceptor

Eya1.hSep097

4

chr1:14264279-14264624

Donor/Acceptor

Eya1.aSep07

35

Gdnf

Isoform 1-2

chr15:7760047-7787580

Alt. 5'/promoter

Gdnf.aSep07

Signal

chr15:7765678-7784357

Donor/Acceptor

Gdnf.bSep07

5

Ret

Ret51 (long)

chr6:118104019-118105315

Retained intron

NM_009050

4

Ret9 (short)

-

Overlapping Exon

NM_001080780

Signal

Wnt11

Isoform A & B

chr7:105983621-106002321

Alt. promoter

Wnt11.cSep07

Signal

chr7:105987691-105994975

Donor/acceptor

Wnt11.cSep07

5

Bmp7

NC

chr2:172693513-172766073

Alt. exon

Bmp7.aSep07

Signal

Pax8

NC

chr2:24298651-24300095

Donor/Acceptor

ENSMUST00000129538

3

Isoform C

chr2:24291401-24291977

Donor/Acceptor

ENSMUST00000102940

8

Six2

NC

chr17:86084844-86086736

Donor

N/A

6

Fgf8

Isoform 2 & 3

chr19:45816160-45816410

Cassette Exon

NM_001166361; NM_001166362

4

Wnt4

NC

chr4:136845255-136851407

Acceptor

Wnt4.bSep07

4