Difference of cell cycle expression pattern across species achieved by either differences in motif content or occupancy by nucleosomes. A. We identified MBP1 sites absent in S. bayanus but present in S. cerevisiae. The nucleosome signal around these sites (left) is compared against the expression profiles (right). B. The S. bayanus orthologous sequences of the functional motif sites from S. cerevisiae were ranked according to whether the downstream genes show a periodic expression pattern during the cell cycle. The nucleosome signal centered at the MBP1 motif (left) and the expression pattern of the downstream genes (right) was plotted.