From: Deciphering c-MYC-regulated genes in two distinct tissues
 |  | Pancreatic β-Cells | Suprabasal Keratinocytes |  | ||||||
---|---|---|---|---|---|---|---|---|---|---|
Gene Symbol | RefSeq | 4 Hours | 8 Hours | 16 Hours | 32 Hours | 4 Hours | 8 Hours | 16 Hours | 32 Hours | Myc-response p-value |
Cell Cycle | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
ccna2 | X75483 | 0.96 | 4.52** | 10.49** | 3.25** | 0.81 | 0.67 | 1.39 | 0.97 | 2.05E-02 |
ccna2 | X75483 | 0.55** | 1.33* | 12.39** | 3.47** | 0.63** | 0.71* | 0.99 | 1.05 | 1.12E-02 |
ccnb1 | NM_007629 | 1.02 | 0.90 | 2.38** | 1.13 | 0.48** | 1.03 | 1.01 | 0.58** | 9.74E-03 |
ccnb1 | NM_007629 | 1.06 | 2.85** | 8.15** | 3.62** | 0.60 | 0.46* | 1.39 | 0.61 | 3.73E-02 |
ccnd1 | NM_007631 | 1.86** | 2.09** | 0.88 | 1.45 | 1.13 | 1.31 | 1.79* | 1.04 | 4.55E-02 |
ccnd1 | NM_007631 | 1.69 | 2.38 | 1.41 | 2.27* | 1.05 | 1.33 | 1.72 | 1.26 | 2.24E-02 |
ccnd1 | NM_007631 | 3.41** | 2.74* | 2.03* | 2.05 | 1.35 | 0.99 | 1.54 | 1.81 | 2.23E-02 |
ccnd2 | NM_009829 | 1.63* | 0.61* | 2.28** | 2.95** | 1.37 | 1.46 | 0.94 | 1.40 | 2.62E-02 |
ccnd2 | NM_009829 | 1.82 | 1.03 | 1.22 | 1.90* | 0.83 | 1.33 | 0.97 | 1.78 | 1.48E-02 |
ccnd2 | NM_009829 | 2.06** | 2.04** | 1.27 | 2.30** | 0.90 | 0.84 | 1.29 | 0.84 | 1.21E-02 |
ccnd2 | AK007904 | 1.99** | 0.64* | 1.88** | 2.62** | 1.66* | 2.57** | 1.00 | 2.13** | 1.28E-03 |
ccnd2 | NM_009829 | 2.09* | 1.00 | 1.06 | 2.01* | 1.26 | 0.96 | 1.12 | 1.51 | 2.38E-02 |
ccnd3 | NM_007632 | 1.26* | 0.84 | 1.54** | 1.20 | 0.81* | 2.58** | 0.84 | 3.33** | 8.71E-04 |
ccne1 | NM_007633 | 1.82** | 3.37** | 7.02** | 1.71* | 0.94 | 1.35 | 1.15 | 1.82** | 2.52E-02 |
ccne1 | BB293079 | 1.83** | 6.68** | 1.87** | 2.04** | 0.85 | 1.50* | 1.16 | 1.29 | 1.02E-02 |
ccne2 | AF091432 | 2.62** | 5.86** | 5.92** | 7.86** | 1.74 | 1.11 | 1.42 | 1.39 | 1.45E-02 |
cdc2a | NM_007659 | 0.95 | 2.91** | 11.93** | 3.35** | 0.51* | 1.17 | 0.89 | 1.12 | 4.33E-02 |
cdc25a | C76119 | 2.71** | 2.23** | 2.09** | 3.90** | 1.11 | 0.46** | 1.07 | 0.78 | 1.84E-03 |
cdc25a | C76119 | 2.17** | 1.73* | 2.03** | 2.10** | 1.02 | 1.14 | 1.1 | 1.21 | 2.45E-02 |
cdk4 | NM_009870 | 1.16 | 0.92 | 8.41** | 1.11 | 1.32 | 12.27** | 0.74 | 1.62 | 2.70E-02 |
cdk4 | NM_009870 | 1.21 | 0.74 | 5.31** | 1.5 | 1.23 | 11.30** | 0.92 | 1.48 | 3.31E-02 |
cdk4 | NM_009870 | 1.20 | 0.88 | 5.03** | 1.3 | 1.37 | 11.17** | 0.72 | 1.37 | 3.45E-02 |
cdk7 | U11822 | 0.63* | 0.77 | 3.69** | 3.45** | 0.82 | 2.12** | 1.09 | 1.59* | 1.37E-02 |
cks2 | NM_025415 | 0.92 | 3.03** | 10.08** | 4.80** | 0.51** | 0.76 | 1.27 | 0.71 | 4.37E-03 |
cks2 | NM_025415 | 0.98 | 2.33** | 8.92** | 2.34** | 0.63* | 0.92 | 0.93 | 1.32 | 1.18E-02 |
pcna | BC010343 | 1 | 2.44** | 17.91** | 4.75** | 1.32 | 3.24** | 0.76 | 3.08** | 3.38E-02 |
pcnt | NM_008787 | 2.70** | 3.79** | 5.22** | 4.18** | 1.14 | 1.89** | 1.10 | 1.82** | 5.43E-06 |
Cell Cycle Arrest | Â | Â | Â | Â | Â | Â | Â | Â | Â | |
cdkn1a | AK007630 | 1.57** | 2.05** | 1.71** | 1.24 | 0.96 | 1.44* | 0.99 | 0.90 | 5.01E-03 |
cdkn1b | NM_009875 | 1.03 | 0.19** | 0.71 | 0.95 | 0.23** | 0.42* | 0.48* | 0.89 | 1.02E-02 |
cdkn2a | NM_009877 | 2.17** | 1.79** | 1.57** | 2.61** | 1.21 | 1.07 | 1.07 | 0.87 | 8.43E-03 |
cdkn2c | BC027026 | 0.32** | 1.18 | 5.62** | 0.59* | 0.85 | 1.28 | 0.87 | 1.60* | 9.38E-03 |
gadd45g | AK007410 | 0.59* | 0.41** | 1.88** | 0.59** | 4.07** | 5.16** | 3.39** | 2.78** | 5.95E-03 |
gas6 | NM_019521 | 0.60** | 0.73** | 1.02 | 0.90 | 1.39** | 2.61** | 1.43** | 5.62** | 2.31E-02 |
ing3 | BB298005 | 0.90 | 1.12 | 1.15 | 0.66** | 0.79 | 0.49** | 0.77* | 1.34* | 1.50E-02 |
Cell Growth and Cytoskeleton Organization | Â | Â | Â | Â | Â | Â | Â | |||
add1 | BF140063 | 0.99 | 0.96 | 1.16 | 0.96 | 0.85 | 2.57** | 0.86 | 3.93** | 1.94E-02 |
add1 | BF140063 | 0.82 | 0.80 | 0.62** | 0.56** | 1.25 | 2.41** | 1.24 | 0.44** | 8.01E-03 |
cap1 | NM_007598 | 4.88* | 0.80 | 1.16 | 1.14 | 1.50 | 8.59** | 0.87 | 0.17** | 4.61E-02 |
cfl1 | NM_007687 | 1.29 | 0.51** | 1.30 | 1.89** | 1.03 | 2.28** | 1.15 | 2.14** | 4.26E-02 |
creg1 | BC027426 | 1.06 | 0.83 | 2.39** | 1.72** | 0.82 | 1.54* | 0.69* | 1.09 | 3.57E-02 |
creg1 | BC027426 | 2.08** | 2.12** | 1.60** | 2.16** | 0.69* | 0.85 | 0.98 | 0.92 | 3.68E-02 |
egf | NM_010113 | 1.05 | 0.79 | 0.92 | 1.38* | 1.62** | 0.47** | 0.91 | 0.84 | 1.28E-02 |
lsp1 | NM_019391 | 0.90 | 0.78* | 0.97 | 1.10 | 1.02 | 3.42** | 0.67** | 1.90** | 3.22E-02 |
myh4 | BG794681 | 0.99 | 1.25 | 0.65 | 1.06 | 1.72 | 2.94* | 0.94 | 1.55 | 8.16E-03 |
pdlim3 | NM_016798 | 1.00 | 1.09 | 1.07 | 0.78 | 0.85 | 2.73** | 1.49* | 2.29** | 4.52E-02 |
plec1 | BM210485 | 1.31 | 0.49* | 1.25 | 3.10** | 0.53 | 1.38 | 1.04 | 2.87** | 2.42E-02 |
plec1 | BM232239 | 1.20 | 0.77 | 1.35 | 2.46** | 3.23** | 4.56** | 2.82** | 0.59* | 2.09E-03 |
tuba3a | NM_009446 | 0.97 | 0.97 | 1.13 | 1.00 | 0.83 | 3.09** | 0.89 | 3.20** | 1.22E-02 |
tubb2c | BC005547 | 1.06 | 1.04 | 4.72** | 1.48* | 1.13 | 2.01** | 1.04 | 1.41* | 3.23E-02 |
tubb6 | NM_026473 | 1.21 | 0.90 | 2.95** | 1.71* | 0.97 | 2.99** | 1.28 | 3.49** | 2.41E-02 |