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Table 3 Panther classification of Biological processes, Molecular functions and Pathways significantly enriched in the set of 37 genes

From: An integrated approach identifies IFN-regulated microRNAs and targeted mRNAs modulated by different HCV replicon clones

 

Observed Genes•

Expected Genes••

p-value•••

BIOLOGICAL PROCESS

   

Cellular process

   

   Establishment or maintenance of chromatin architecture

4

0.55

2.12E-03

Cellular component organization

   

   Organelle organization

4

0.59

2.85E-03

Transport

   

   Intracellular protein transport

9

2.98

2.16E-03

   Vesicle-mediated transport

7

2.10

4.26E-03

   Endocytosis

4

1.04

1.96E-02

System process

   

   Neurotransmitter secretion

3

0.63

2.45E-02

MOLECULAR FUNCTION

   

Catalytic activity

   

   GTPase activity

3

0.52

1.53E-02

Enzyme regulator activity

   

   Peptidase inhibitor activity

2

0.32

4.08E-02

Binding

   

   Chromatin binding

2

0.34

4.59E-02

PATHWAYS

   

Ubiquitin proteasome pathway

2

0.13

7.19E-03

  1. • Number of genes, in the dataset of 37, that map to the indicated Panther classification categories
  2. •• Expected number of genes, in the dataset of 37, based on the NCBI reference list of human genome
  3. ••• p-value as determined by the binomial statistic. A cutoff of 0.05 has been applied
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BMC Genomics

ISSN: 1471-2164

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