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Table 1 List of predicted primary targets of Ahr.

From: Transcriptional signatures of regulatory and toxic responses to benzo-[a]-pyrene exposure

MGI ID

cluster votes

target votes

train/test

MGI ID

cluster votes

target votes

train/test

Hspa4l

1.00

0.98

test

Ccng2

0.98

0.9

test

2410066E13Rik

1.00

0.98

test

Fam198b

0.98

0.9

test

Arl6ip5

1.00

0.98

test

Ddit4

0.98

0.9

test

Plscr2

1.00

0.98

test

Ubl3

0.98

0.87

test

Mpp2

1.00

0.98

training

Nqo1

0.98

0.87

test

Tiparp

1.00

0.98

training

Trp53inp1

0.98

0.87

test

Sdpr

1.00

0.98

test

Cyp1a1

0.98

0.86

test

Ndrg1

1.00

0.97

test

Abca6

0.98

0.86

test

Nrn1

1.00

0.97

test

Hmox1

0.98

0.83

test

Cyp2s1

1.00

0.97

test

Aldh4a1

0.98

0.81

test

Tnfaip2

1.00

0.97

test

Npffr1

0.97

0.91

test

Cpox

1.00

0.97

training

Btg2

0.97

0.89

test

Osbpl2

1.00

0.97

test

Nr3c1

0.97

0.87

test

Rbks

1.00

0.96

test

Gm10122

0.97

0.87

test

Ppard

1.00

0.96

training

Snx30

0.96

0.96

training

Tbc1d16

1.00

0.95

test

Cdkn1b

0.96

0.92

test

Arrdc3

1.00

0.95

training

Slc26a2

0.96

0.88

test

Lpin1

1.00

0.95

test

Plk2

0.96

0.85

test

Id2

1.00

0.94

test

Zscan29

0.96

0.83

test

Xdh

1.00

0.94

test

Zfp608

0.95

0.92

training

Gramd3

1.00

0.94

test

Nrg1

0.95

0.91

test

Serpine1

1.00

0.93

test

Abcd2

0.95

0.8

test

Pfkfb3

0.99

0.98

training

Klf9

0.94

0.94

test

Jub

0.99

0.97

test

Dusp1

0.94

0.92

training

Ddx58

0.99

0.97

training

Tnfaip8

0.94

0.88

test

Zfp418

0.99

0.95

test

9330175E14Rik

0.94

0.82

test

Sgk1

0.99

0.94

test

Lrrc30

0.93

0.89

test

Jun

0.99

0.93

test

Eda2r

0.93

0.85

test

Cdkn1a

0.99

0.92

test

Bmf

0.92

0.93

test

Abcc4

0.99

0.91

test

Rnf39

0.91

0.92

training

Slc6a9

0.99

0.91

test

St6gal1

0.9

0.94

training

Adh7

0.99

0.90

test

Zfp36l1

0.89

0.83

test

Usp18

0.99

0.90

test

Nr1d1

0.86

0.91

training

Npc1

0.99

0.88

test

Irs2

0.86

0.91

test

Casp3

0.99

0.87

test

Ets2

0.84

0.86

training

Aldh3a1

0.99

0.86

test

Nfe2l2

0.78

0.86

test

Slc35d1

0.99

0.85

test

Irf1

0.76

0.91

training

Cyp1b1

0.98

0.97

test

Cib2

0.71

0.84

test

Intu

0.98

0.95

training

S1pr1

0.7

0.89

training

Pitpnc1

0.98

0.95

training

Traf5

0.59

0.89

training

Sesn2

0.98

0.92

training

    
  1. List of predicted primary targets of Ahr transcriptional regulation. Confidence scores of both membership in cluster 3 (cluster votes) and as a primary Ahr target (target votes) are given. Known transcriptional regulators (i.e. annotated with relevant GO terms) are bolded. Additionally, assignment to either the training or test set is indicated for each gene.