Figure 2
From: A genome-wide survey for SNPs altering microRNA seed sites identifies functional candidates in GWAS
Four SNPs found to associate, or be in LD with a SNP that associates, with a trait(s) relevant to disease. Each panel depicts the mRNA-miR interaction and the effect of the SNP on this interaction. Plots were generated using the Genvar web tool and published expression data from Nica, et al. rho = correlation between genotype and transcript levels. p = t = test statistic for correlation. padj = adjusted pvalue for correlation. F = -Fat cell biopsy (n = 160), L = LCL cells (n = 166), and S = skin cell biopsy (n = 160). Twin1 = Unrelated twin group 1. Twin2 = unrelated twin group 2.