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Table 3 List of top 50 genes significantly differentially regulated in liver based on fold difference (t-test).

From: Gene expression profiling in the Cynomolgus macaque Macaca fascicularis shows variation within the normal birth range

Gene Symbol 2Way ANOVA P value Fold Change in Liver Welch t-test Regulation in LBW Fold change skeletal tissue, Welch t-test Regulation in LBW Fold change in Cords, Welch t-test Regulation in LBW Gene name
ELMOD1 0.011425177 25.931845 down 1.737314 down 2.051013 up Homo sapiens ELMO/CED-12 domain containing 1 (ELMOD1), mRNA [NM_018712]
RBBP9 0.026729036 11.012514 down 1.47388 down 5.131376 down Homo sapiens retinoblastoma binding protein 9 (RBBP9), mRNA [NM_006606]
MMP25 0.001325307 10.996225 down 2.384582 down 1.436251 down Homo sapiens matrix metallopeptidase 25 (MMP25), mRNA [NM_022468]
C5orf46 0.047762383 10.762607 down 1.234639 up 1.096919 up Homo sapiens similar to AVLV472 (MGC23985), mRNA [NM_206966]
GOLSYN 2.29E-05 6.13113 up 1.05566 up 1.458383 up Homo sapiens hypothetical protein FLJ20366 (FLJ20366), mRNA [NM_017786]
LCN15 0.005291665 5.3478875 up 1.891747 up 2.217465 up Homo sapiens MSFL2541 (UNQ2541), mRNA [NM_203347]
CCDC146 0.030661521 5.281487 up 1.06658 up 1.360575 up Homo sapiens KIAA1505 protein (KIAA1505), mRNA [NM_020879]
AK094929 0.001118242 5.262121 up 1.690864 up 1.110624 up Homo sapiens cDNA FLJ37610 fis, clone BRCOC2011398. [AK094929]
SORCS3 0.00328917 5.0026994 up 2.266284 up 2.921157 up Homo sapiens sortilin-related VPS10 domain containing receptor 3 (SORCS3), mRNA [NM_014978]
COL4A4 0.01571377 4.897748 down 1.548386 down 1.059327 down Homo sapiens collagen, type IV, alpha 4 (COL4A4), mRNA [NM_000092]
IL1R2 0.004347455 4.777918 down 1.8715 down 1.690538 down Homo sapiens interleukin 1 receptor, type II (IL1R2), transcript variant 1, mRNA [NM_004633]
CD200R1 0.04967409 4.7169123 down 1.052303 up 1.319852 down Homo sapiens CD200 receptor 1 (CD200R1), transcript variant 1, mRNA [NM_138806]
GTSF1 0.017040279 4.653995 up 3.663281 up 2.487166 up Homo sapiens family with sequence similarity 112, member B (FAM112B), mRNA [NM_144594]
SNAI1 0.005038617 4.582946 down 1.534132 down 1.847129 down Homo sapiens snail homolog 1 (Drosophila) (SNAI1), mRNA [NM_005985]
USH1C 0.00505742 4.3276477 up 1.595945 up 1.465964 up Homo sapiens Usher syndrome 1C (autosomal recessive, severe) (USH1C), transcript variant 1, mRNA [NM_005709]
ALLC 0.006709512 4.060955 up 1.861818 up 2.766094 up Homo sapiens allantoicase (ALLC), transcript variant 1, mRNA [NM_018436]
CXCL3 0.04903758 3.9091544 down 1.096309 down 1.172056 up Homo sapiens chemokine (C-X-C motif) ligand 3 (CXCL3), mRNA [NM_002090]
XR_014204 0.029225934 3.8491352 down 3.167453 down 1.084816 up PREDICTED: Macaca mulatta hypothetical protein LOC719546 (LOC719546), mRNA [XR_014204]
XR_011794 0.010519872 3.637105 up 3.785519 up 2.76764 up PREDICTED: Macaca mulatta similar to poly(A)-specific ribonuclease (PARN)-like domain containing 1 (LOC707835), mRNA [XR_011794]
NMNAT2 0.045685206 3.6255727 up 2.521069 down 2.189285 up Homo sapiens nicotinamide nucleotide adenylyltransferase 2 (NMNAT2), transcript variant 1, mRNA [NM_015039]
SLC39A8 0.041505713 3.6139402 down 1.366996 down 1.390711 down Homo sapiens solute carrier family 39 (zinc transporter), member 8 (SLC39A8), mRNA [NM_022154]
CA2 0.033340864 3.4830022 down 3.573662 down 1.194329 up Homo sapiens carbonic anhydrase II (CA2), mRNA [NM_000067]
NTRK3 0.003890598 3.4711208 up 1.593136 up 1.043792 down Homo sapiens neurotrophic tyrosine kinase, receptor, type 3 (NTRK3), transcript variant 1, mRNA [NM_001012338]
C17orf75 0.001362531 3.4477015 down 3.758336 down 1.443745 down Homo sapiens chromosome 17 open reading frame 75 (C17orf75), mRNA [NM_022344]
CXCL1 0.006956845 3.392382 down 1.063934 up 4.611126 down Homo sapiens chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) (CXCL1), mRNA [NM_001511]
NM_198692 0.03194352 3.3605232 down 1.343767 up 1.654617 down Homo sapiens keratin associated protein 10-11 (KRTAP10-11), mRNA. [NM_198692]
SHANK2 0.023280138 3.3547363 up 1.255762 up 1.189415 down Homo sapiens SH3 and multiple ankyrin repeat domains 2 (SHANK2), transcript variant 1, mRNA [NM_012309]
CCDC81 0.004982437 3.2717588 down 1.533572 down 4.912844 down Homo sapiens coiled-coil domain containing 81 (CCDC81), mRNA [NM_021827]
CCL11 0.008992519 3.1781478 down 4.050988 down 1.002582 up Homo sapiens chemokine (C-C motif) ligand 11 (CCL11), mRNA [NM_002986]
CO647386 0.020776557 3.1651435 down 1.030158 down 1.631509 down ILLUMIGEN_MCQ_40418 Katze_MMPB2 Macaca mulatta cDNA clone IBIUW:21432 5' similar to Bases 185 to 778 highly similar to human CXCL2 (Hs.75765), mRNA sequence [CO647386]
GPR98 0.024752488 3.1570897 down 1.10821 down 3.919889 down Homo sapiens G protein-coupled receptor 98 (GPR98), transcript variant 1, mRNA [NM_032119]
TMEM59L 5.34E-04 3.137047 up 1.57364 up 1.407988 up Homo sapiens transmembrane protein 59-like (TMEM59L), mRNA [NM_012109]
UGT1A6 0.040070046 3.1353552 down 2.066639 down 1.399845 down Homo sapiens UDP glucuronosyltransferase 1 family, polypeptide A6 (UGT1A6), transcript variant 1, mRNA [NM_001072]
KCNE2 7.02E-04 3.1135461 up 1.972823 up 1.170852 down Homo sapiens potassium voltage-gated channel, Isk-related family, member 2 (KCNE2), mRNA [NM_172201]
XR_012376 0.022554293 3.0699794 down 1.9303 down 1.439485 down PREDICTED: Macaca mulatta hypothetical protein LOC710335 (LOC710335), mRNA [XR_012376]
RXFP1 0.002097808 3.0400152 up 1.931833 up 1.276558 up Homo sapiens relaxin/insulin-like family peptide receptor 1 (RXFP1), mRNA [NM_021634]
ITGBL1 0.02861261 3.0041916 down 2.563332 down 1.243521 down Homo sapiens integrin, beta-like 1 (with EGF-like repeat domains) (ITGBL1), mRNA [NM_004791]
PASK 0.03426426 2.995584 up 5.977056 up 19.17474 up Homo sapiens PAS domain containing serine/threonine kinase (PASK), mRNA [NM_015148]
DEFB1 0.004949556 2.9797235 down 1.065357 up 2.807533 down Homo sapiens defensin, beta 1 (DEFB1), mRNA [NM_005218]
WDR8 0.004681234 2.9781044 down 5.68043 down 8.061375 down Homo sapiens WD repeat domain 8 (WDR8), mRNA [NM_017818]
RIMS4 0.04112827 2.9677074 up 1.724443 up 1.024011 down Homo sapiens regulating synaptic membrane exocytosis 4 (RIMS4), mRNA [NM_182970]
PDGFRL 0.011396675 2.9371088 down 1.21306 down 1.55284 down Homo sapiens platelet-derived growth factor receptor-like (PDGFRL), mRNA [NM_006207]
TNRC4 0.005930619 2.9251838 up 1.208589 up 1.396738 up Homo sapiens trinucleotide repeat containing 4 (TNRC4), mRNA [NM_007185]
UGT2B11 0.02518766 2.9193914 down 1.09908 down 2.958316 down Homo sapiens UDP glucuronosyltransferase 2 family, polypeptide B11 (UGT2B11), mRNA [NM_001073]
FLT3LG 0.029793594 2.8908129 up 1.037797 down 1.527226 up Homo sapiens fms-related tyrosine kinase 3 ligand (FLT3LG), mRNA [NM_001459]
IP6K3 0.03900314 2.8685477 up 1.471319 up 1.39455 down Homo sapiens inositol hexaphosphate kinase 3 (IHPK3), mRNA [NM_054111]
ST6GALNAC1 0.03669531 2.8622296 down 1.408642 down 2.126189 down Homo sapiens ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 (ST6GALNAC1), mRNA [NM_018414]
EFNA4 0.007086268 2.843187 down 1.084758 up 2.766163 down Homo sapiens ephrin-A4 (EFNA4), transcript variant 1, mRNA [NM_005227]
MYST3 0.013409907 2.827006 up 3.302978 up 1.403819 up Homo sapiens MYST histone acetyltransferase (monocytic leukemia) 3 (MYST3), mRNA [NM_006766]
XM_370715 0.001614059 2.7565975 up 1.561267 up 2.382949 up PREDICTED: Homo sapiens similar to hypothetical protein MGC48915 (LOC387911), mRNA [XM_370715]
NM_031436 0.035783853 2.6903787 up 1.740635 up 1.698687 up Homo sapiens aldo-keto reductase family 1, member C-like 2 (AKR1CL2), mRNA. [NM_031436]