From: Deep sequencing-based analysis of the anaerobic stimulon in Neisseria gonorrhoeae
Gene | ORF designation | Â | Â | Â | Definition |
---|---|---|---|---|---|
Common elements of the anaerobic and iron responsive stimulon | |||||
 |  | -O2/+O2a | -Fe/+Feb |  |  |
farR | NGO0058 | 3.9 | -2.0 | Â | MarR family transcriptional regulator |
gluP | NGO0142 | -3.7 | 2.9 | Â | Glucose/galactose transporter |
nhaC | NGO0143 | -3.1 | -2.3 | Â | Na+/H+ antiporter (NhaC) |
amtB | NGO0198 | -4.3 | -14.2 | Â | Ammonium transporter AmtB |
nspA | NGO0233 | -3.4 | 2.6 | Â | Outer membrane protein |
greB | NGO0262 | -4.5 | -1.8 | Â | Transcription elongation factor |
 | NGO0373 | -7.4 | -2.5 |  | Amino acid ABC transporter, permease protein |
 | NGO0377 | -7.4 | -150.4 |  | Probable transmembrane transport protein |
cspA | NGO0410 | -3.6 | 3.2 | Â | Cold shock protein A |
 | NGO0492 | 7.7 | 1.8 |  | Putative phage associated protein |
 | NGO0506 | 13.6 | -3.2 |  | Putative phage associated protein |
 | NGO0635 | -4.2 | 4.2 |  | Hypothetical protein |
lldD | NGO0639 | -9.1 | 3.9 | Â | L-lactate dehydrogenase |
pdxH | NGO0658 | 4.9 | 1.8 | Â | Pyridoxamine 5-phosphate oxidase |
eda | NGO0713 | -4.3 | 6.9 | Â | KHG-KDPG bifunctional aldolase |
 | NGO0732 | 2.8 | 2.7 |  | Neisseria-specific protein |
mobA | NGO0754 | 4.1 | 3.2 | Â | Molybdopterin-guanine dinucleotide biosynthesis protein |
 | NGO0757 | 3.4 | 2.2 |  | Putative periplasmic Cpx-family sensor kinase |
bfrA | NGO0794 | 12.0 | -2.8 | Â | Bacterioferritin A |
bfrB | NGO0795 | 9.9 | -1.9 | Â | Bacterioferritin B |
hslR | NGO0822 | 3.9 | 2.4 | Â | Heat shock protein (Hsp15) |
 | NGO0895 | 5.5 | 1.8 |  | Neisseria-specific protein, uncharacterized |
sdhA | NGO0921 | -3.6 | -2.3 | Â | Succinate dehydrogenase flavoprotein subunit |
sdhC | NGO0923 | -3.0 | -2.3 | Â | Succinate dehydrogenase, cytochrome b556 chain |
 | NGO0995 | 3.2 | 1.9 |  | Neisseria-specific protein, uncharacterized |
hsp33 | NGO1189 | 5.7 | -2.9 | Â | Heat shock protein Hsp33 chaperonin |
 | NGO1261 | -6.7 | 3.4 |  | S-adenosylmethionine-dependent methyltransferase |
lldP | NGO1361 | -8.7 | -3.2 | Â | L-lactate permease |
nqrB | NGO1414 | -6.7 | -2.7 | Â | Sodium-translocating NADH-ubiquinone reductase subunit B |
nqrC | NGO1415 | -6.3 | -2.1 | Â | Sodium-translocating NADH-ubiquinone reductase subunit C |
nqrE | NGO1417 | -8.4 | -5.5 | Â | Sodium-translocating NADH-ubiquinone reductase subunit E |
nqrF | NGO1418 | -6.4 | -3.1 | Â | Sodium-translocating NADH-ubiquinone reductase subunit F |
putP | NGO1552 | -8.3 | -5.3 | Â | Sodium/proline symporter PutP |
ompA | NGO1559 | 3.6 | 2.5 | Â | Probable outer membrane protein |
arsR | NGO1562 | 4.2 | -2.3 | Â | ArsR family transcriptional regulator |
 | NGO1628 | 6.3 | 2.1 |  | Conserved hypothetical protein |
 | NGO1633 | 82.1 | 2.1 |  | Putative phage associated protein |
 | NGO1688 | -3.1 | 3.7 |  | Conserved hypothetical protein |
folA | NGO1694 | 3.3 | -2.0 | Â | Dihydrofolate reductase (FolA) |
 | NGO1807 | -3.3 | -3.0 |  | Amino-acid transporter |
dadA | NGO1808 | -4.4 | -2.9 | Â | D-amino acid dehydrogenase small subunit (DadA) |
yhhF | NGO1860 | 3.9 | 2.2 | Â | Probable DNA methylase Symport protein (possible sodium/dicarboxylate |
 | NGO1957 | -7.8 | -2.0 |  | symporter) |
 | NGO2023 | 4.9 | 1.9 |  | Conserved hypothetical protein |
sspB | NGO2131 | -4.1 | 3.3 | Â | Stringent starvation protein B |
 | nrrF | -6.2 | 170†|  | Fur regulated small regulatory RNA |
Common elements of the anaerobic and hydrogen peroxide responsive stimulon | |||||
 |  | -O2/+O2 | +HP/-HPc |  |  |
recN | NGO0318 | 5.1 | 3.0 | Â | DNA repair protein RecN (recombination protein N) |
dnaB | NGO0485 | 5.2 | 6.5 | Â | Replicative DNA helicase |
nmlR | NGO0602 | 7.4 | -4.8 | Â | Transcriptional regulator MerR-family |
nifU | NGO0633 | -5.0 | 4.6 | Â | Fe-S scaffold protein |
iscS | NGO0636 | -5.2 | 4.1 | Â | Cysteine desulferase |
leu1 | NGO0848 | 5.6 | 3.3 | Â | 2-isopropylmalate synthase |
aniA | NGO1276 | 28.2 | -3.6 | Â | Copper-containing dissimilatory nitrite reductase |
grpE | NGO1422 | 3.2 | 5.8 | Â | Heat shock protein (HSP-70 cofactor) |
lexA | NGO1427 | 4.8 | 6.3 | Â | Transcriptional regulator, repressor |
 | NGO1428 | 11.4 | 3.9 |  | Neisseria-specific protein, uncharacterized |
dnaK | NGO1429 | 3.1 | 10.8 | Â | Heat shock protein (HSP-70 chaperone) |
ccp | NGO1769 | 8.9 | 2.7 | Â | Probable cytochrome c peroxidase |
dnaJ | NGO1901 | 4.0 | 3.0 | Â | Heat shock protein HSP-40/chaperone DnaJ |
Common elements of the anaerobic, iron, and hydrogen peroxide responsive stimulon | |||||
 |  | -O2/+O2 | -Fe/+Fe | +HP/-HP |  |
 | NGO0108 | -4.9 | 4.7 | 6.8 | Conserved hypothetical protein (possible oxidoreductase) |
glr3 | NGO0114 | 5.0 | 4.7 | 4.8 | Glutaredoxin 3 |
fbpA | NGO0217 | -5.2 | 8.7 | 5.5 | Periplasmic iron-binding protein |
 | NGO0554 | -4.8 | 24.5 | 70.6 | Hypothetical protein |
trx1 | NGO0652 | -5.8 | 3.2 | 13.5 | Thioredoxin I |
fumC | NGO1029 | -4.6 | 6.4 | 8.4 | Fumarate hydratase (fumarase C) |
clpB | NGO1046 | 7.2 | 4.3 | 23.8 | Endopeptidase ClpB (heat shock protein) |
pgm | NGO1258 | -4.8 | 2.0 | 2.8 | Phosphoglycerate mutase |
hemO | NGO1318 | -9.8 | 8.4 | 9.8 | Heme oxygenase/iron starvation protein |
exbD | NGO1377 | -3.5 | 3.9 | 4.4 | Transport protein (ExbD) |
exbB | NGO1378 | -4.1 | 6.5 | 4.7 | Transport protein (ExbB) Sodium-translocating NADH-ubiquinone reductase |
nqrA | NGO1413 | -5.8 | -2.3 | -2.6 | subunit A |
 |  |  |  |  | Sodium-translocating NADH-ubiquinone reductase |
nqrD | NGO1416 | -10.3 | -4.0 | -2.8 | subunit D |
lecA | NGO1981 | 4.5 | 2.5 | 2.5 | Adhesin protein |