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Table 1 Three-way analysis of RNAi treatments performed on Bristol (N2) and Hawaii (CB4856)

From: A fitness assay for comparing RNAi effects across multiple C. elegans genotypes

gene targeted

EV vs Target in Bristol

EV vs Target in Hawaii

P value (Bristol vs Hawaii)

ev

-

-

0.15

mpk-1

0.80

0.86

0.10

smo-1

9.80E-06

0.74

5.30E-08

par-1

0.04 1

0.74

0.0013

lin-31

0.50

0.35

0.097

let-502

0.09

0.50

0.03

gld-1

0.039

0.79

1.30E-06

par-6

0.022

0.36

0.0025

pos-1

0.007 1

0.67

9.20E-06

rab-5

6.10E-33

4.50E-36

0.23

mel-26

2.18E-09

0.93

1.70E-14

tag-214

2.56E-16

4.90E-29

8.90E-15

  1. The second column indicates differences that can be detected between the RNAi treatment and the control (ev) in Bristol. P values are derived from time points 5 to 9 except for 1, in which time points 6 to 8 were used (see summary statistics). The third column indicates differences that can be detected between the RNAi treatment and the control (ev) in Hawaii. The last column is a comparison between Bristol and Hawaii.