Schematic representation of the respiratory pathway in Helicobacter bizzozeronii CIII-1. In red the reactions predicted to be present in H. bizzozeronii CIII-1 but not in H. pylori. In black the reactions predicted to be in common in both Helicobacter species. In blue TMAO/DMSO reduction which could be predicted also in H. pylori but a complete set of enzyme is not present. The arrows indicate the direction of the electrons to or from the membrane-bound electron transport chain. Dashed lines indicate that the direction of the electrons is unknown. Enzymes catalyzing key reactions are indicated in boxes. FDH, formate dehydrogenase; HYD, hydrogenase; NRS, nitrite reductase system; SNO, S- and N- oxidases; GDH, glycerol-3-phosphate dehydrogenase; NDH, NAD(P)H dehydrogenase; SDH/FR, succinate dehydrogenase/fumarate reductase; MQR, malate-quinone-reductase; LDH, lactate dehydrogenase; GLC, glycol oxidase; NAP, periplasmic nitrate reductase; Q, quinone; Cyt b/c1, quinone cytochrome oxidoreductase; Cyt c, cytochrome c; cbb3, cytochrome c oxidase; ccP, cytochrome c peroxidase.