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Table 3 Top functions by pathway analysis (IPA)

From: HMGA1 drives stem cell, inflammatory pathway, and cell cycle progression genes during lymphoid tumorigenesis

  CAM Partek Overlaps CAM Partek Overlaps
  2months 2months 2months 12months 12months 12months
Disease & Disorder-related Function Inflammatory response Inflammatory response *Inflammatory response Cancer Cancer Cancer
  3.57 × 10-5 - 0.0320 1.61 × 10-5 - 0.0474 1.93 × 10-4 - 0.0474 2.71 × 10-7 -6.96 × 10-3 2.84 × 10-6 -3.44 × 10-3 1.77 × 10-5 -.0133
Molecular & Cellular Functions *Cellular development *Cellular function & maintenance Cell-to-cell signaling & interaction *Cellular development *Cell cycle *Cell cycle
  3.58 × 10-7 -0.0326 1.87 × 10-6 - 0.0444 1.93 × 10-4 - 0.0488 7.10 × 10-13 -7.58 × 10-3 1.23 × 10-11 - 3.09 × 10-3 2.32 × 10-8 -.0133
Physiological System Development & Function Hematological system development & function Hematological system development & function Hematological system development & function Hematological system development & function Cell-mediated immune response Hematological system development & function
  3.06 × 10-5 -0.0326 2.62 × 10-6 -0.0474 1.93 × 10-4 -0.0485 1.89 × 10-12 -7.26 × 10-3 1.27 × 10-7 -3.09 × 10-3 3.02 × 10-6 -.0133
  1. The top functions identified by Ingenuity Pathway Analysis from each category are shown and include: 1.) Diseases and Disorder-related Function, 2.) Molecular and Cellular Functions, and, 3.) Physiological System Development and Function. * denotes the top biologic function, defined as the function from all 3 categories with the most significant IPA score.