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Table 3 Unique genes with increased expression in spleen after SGIV infection

From: Transcriptome analysis of orange-spotted grouper (Epinephelus coioides) spleen in response to Singapore grouper iridovirus

Gene name species expression in normal Expression in infection Fisher p_value
Profilin-2 Rattus norvegicus 305 29051 0
60S ribosomal protein Homo sapiens 251 23569 0
Eotaxin Mus musculus 3169 17689 0
Granulins Rattus norvegicus 1141 15720 0
Leukocyte cell-derived chemotaxin-2 Mus musculus 4809 10637 0
Thioredoxin Ictalurus punctatus 542 7343 0
Saposin-C Cavia porcellus 43 5116 0
Cystatin-B 1 Macaca fuscata 92 4388 0
Perforin-1 Mus musculus 105 4097 0
Scavenger receptor cysteine-rich type 1 protein Canis familiaris 911 3958 0
Eukaryotic translation initiation factor 4 gamma 2 Gallus gallus 573 3829 0
Gamma-glutamyl hydrolase Homo sapiens 133 2638 0
Legumain Bos taurus 445 2572 0
Proteasome subunit alpha type-7 Carassius auratus 35 2452 0
Glyceraldehyde 3-phosphate dehydrogenase, Danio rerio 103 1983 0
Transcription factor BTF3 Mus musculus 83 1770 0
Src-like-adapter Mus musculus 84 1371 2.02E-303
Keratin 8 Gallus gallus 182 1586 5.86E-283
Galectin-3-binding protein B Danio rerio 450 2187 8.23E-277
SUMO-conjugating enzyme Xenopus tropicalis 137 1307 8.94E-243
C-C motif chemokine 18 Macaca mulatta 282 1667 3.00E-242
Galectin-3-binding protein A Danio rerio 371 1747 3.37E-216
Hemoglobin subunit beta-1 Pseudaphritis urvillii 241 1383 1.38E-197
Keratin 18 Oncorhynchus mykiss 1661 3701 7.37E-180
Eukaryotic translation initiation factor 3 Bos taurus 67 844 4.27E-174
Cytochrome b Tropheus moorii 6544 9945 1.29E-163
Natural killer cell protease 1 Rattus norvegicus 227 1138 1.95E-148
T-complex protein 1 Gallus gallus 50 669 6.61E-141
RNA-binding protein 5 Xenopus tropicalis 45 605 7.97E-128
Cathepsin H Sus scrofa 391 1347 3.79E-125
Beta-2-glycoprotein 1 Bos taurus 433 1389 7.97E-119
Dipeptidyl peptidase 1 Bos taurus 55 586 1.36E-114
Proto-oncogene vav Mus musculus 98 693 8.51E-113
Proteasome subunit alpha type-4 Homo sapiens 684 1761 2.56E-111
Actin-related protein 2/3 complex subunit 5 Mus musculus 90 656 1.35E-108
Proteasome subunit beta type-6-B like Salmo salar 469 1361 8.49E-103
RING-box protein 2 Mus musculus 42 497 3.76E-101
NADH-ubiquinone oxidoreductase chain 1 Carassius auratus 330 1102 2.68E-99
Phospholipid hydroperoxide glutathione peroxidase Sus scrofa 590 1527 1.66E-97
Retinol-binding protein 1 Bos taurus 164 767 1.80E-95
NudC domain-containing protein 2 Rattus norvegicus 81 576 3.36E-94
Lysozyme g Epinephelus coioides 164 742 5.02E-90
Voltage-gated hydrogen channel 1 Danio rerio 217 742 4.09E-69
Ubiquitin-like modifier-activating enzyme 5 Xenopus laevis 179 670 8.17E-69
LRR and PYD domains-containing protein 1 Homo sapiens 205 714 6.02E-68
Cytochrome c oxidase subunit 6B1 Tarsius syrichta 60 395 2.33E-62
Ig lambda chain Homo sapiens 31 315 2.99E-61
Interleukin-8 Equus caballus 155 572 4.14E-58
Fibroleukin Homo sapiens 611 1281 3.75E-56
Rho GDP-dissociation inhibitor 1 Macaca fascicularis 325 844 4.69E-55
Ependymin Notemigonus crysoleucas 70 386 5.52E-55
Fucolectin-4 Anguilla japonica 1519 2434 1.29E-50
Complement factor H Homo sapiens 131 459 1.88E-44
Eukaryotic initiation factor 4A-III Xenopus tropicalis 56 282 4.32E-38
Cysteine and glycine-rich protein 2 Mus musculus 61 290 1.68E-37
Proliferating cell nuclear antigen Haplochromis burtoni 237 575 3.64E-34
Secernin-3 Danio rerio 64 277 2.42E-33
Ubiquitin-conjugating enzyme E2 Mus musculus 74 286 4.09E-31
Heat shock cognate 71 kDa protein Oryzias latipes 25 181 8.31E-31