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Figure 4 | BMC Genomics

Figure 4

From: Human native lipoprotein-induced de novo DNA methylation is associated with repression of inflammatory genes in THP-1 macrophages

Figure 4

Expression of DNMTs and DICER1 in THP-1 macrophages. A, Affymetrix present/absent calls (P and A, respectively) and average normalized probeset intensity are shown for arrays (grouped in triplicates) addressing the effects of VLR. ATP6VOC and APOB are included as examples of a highly expressed and silent gene, respectively. VLR1 through VLR3, independent VLR preparations. B, Immunoblot analysis of DNMT and DICER1 expression. VLDL was used at 91.1 μg protein/ml concentration. Representative alpha-actin immunoreactivity using peripheral blood mononuclear cells as positive control is shown.

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BMC Genomics

ISSN: 1471-2164

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