Table 2 Total of 13 previously detected CNVs (from the Database of Genomic Variants) with breakpoints located to the paralogous subunits (see Figure 7A)
From: Characterization of the past and current duplication activities in the human 22q11.2 region
Index | CNV start | CNV End | Length (bp) | Gain/Loss | Left subunit | Right subunit | Subunit family ID | Block | Technology |
|---|---|---|---|---|---|---|---|---|---|
1 | 17108337 | 17249642 | 141305 | Gain | 17106814-17116867 | 17241175-17251240 | 80 | LCR22-2' | aCGH |
2 | 17108337 | 17249642 | 141305 | Loss | 17106814-17116867 | 17241175-17251240 | 80 | LCR22-2' | aCGH |
3 | 21346546 | 21412512 | 65966 | Loss | 21344443-21350044 | 21410029-21415309 | 42 | LCR22-5' | sequencing |
4 | 21350920 | 21372688 | 21768 | Loss | 21350334-21351679 | 21371980-21373335 | 52 | LCR22-5' | sequencing |
5 | 21359730 | 21420692 | 60962 | Loss | 21359721-21367895 | 21420384-21428665 | 58 | LCR22-5' | sequencing |
6 | 21364900 | 21425105 | 60205 | Loss | 21359721-21367895 | 21420384-21428665 | 58 | LCR22-5' | sequencing |
7 | 21378929 | 21437071 | 58142 | Loss | 21376652-21382799 | 21434410-21440989 | 94 | LCR22-5' | sequencing |
8 | 21381357 | 21439879 | 58522 | Loss | 21376652-21382799 | 21434410-21440989 | 94 | LCR22-5' | sequencing |
9 | 21430381 | 21494380 | 63999 | Loss | 21429486-21431884 | 21493407-21495966 | 71 | LCR22-5' | sequencing |
10 | 22245900 | 22313362 | 67462 | Loss | 22244487-22248921 | 22309895-22314095 | 98 | LCR22-6' | Paired End Mapping |
11 | 22247409 | 22311770 | 64361 | Loss | 22244487-22248921 | 22309895-22314095 | 98 | LCR22-6' | aCGH |
12 | 22291744 | 22295976 | 4232 | Loss | 22288656-22292395 | 22292394-22296670 | 6 | LCR22-6' | sequencing |
13 | 22626028 | 22660855 | 34827 | Loss | 22621224-22626431 | 22659321-22664520 | 8 | LCR22-7' | aCGH |