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Table 4 Most abundant biological process GO annotations of nucleolar-associated proteins with reliability index above 10

From: PNAC: a protein nucleolar association classifier

Biological process GO term Protein counta
Nucleolar-Enriched
RNA metabolic process (GO:0016070) 163
   of which rRNA processing (GO:0006364) 35
tRNA processing (GO:0008033) 27
Transcription, DNA-dependent (GO:0006351) 35
Cellular component organization (GO:0016043) 81
Ribosome biogenesis (GO:0042254) 50
   of which rRNA processing (GO:0006364) 35
Regulation of biological process (GO:0050789) 45
Nucleoplasmic-nucleolar
Nucleobase, nucleoside, nucleotide and nucleic acid metabolic process (GO:0006139) 118
   of which DNA repair (GO:0006281) 52
DNA replication (GO:0006260) 43
Regulation of biological process (GO:0050789) 107
   of which Regulation of transcription, DNA-dependent (GO:0006355) 35
Signal transduction (GO:0007165) 36
Cellular component organization (GO:0016043) 92
   of which Chromosome organisation (GO:0051276) 68
Cell cycle (GO:0007049) 89
Multicellular organismal development (GO:0007275) 40
Cell proliferation (GO:0008283) 39
Cell death (GO:0008219) 27
Nucleolar-cytoplasmic
Protein metabolic process (GO:0019538) 127
   of which Translation (GO:0006412) 106
Nucleobase, nucleoside, nucleotide and nucleic acid metabolic process (GO:0006139) 33
Regulation of biological process (GO:0050789) 27
   of which Signal transduction (GO:0007165) 10
Cellular component organisation (GO:0016043) 18
   of which Organelle organisation (GO:0006996) 11
  1. a count includes proteins annotated with child terms