Skip to main content
Figure 2 | BMC Genomics

Figure 2

From: Differential gene expression in liver and small intestine from lactating rats compared to age-matched virgin controls detects increased mRNA of cholesterol biosynthetic genes

Figure 2

Plot of Mean Intensities for Known Cholesterol Biosynthetic Enzymes. The mean untransformed intensities were plotted against tissue/physiologic state combination. C and L indicate the mean of Control and Lactating samples, respectively, within each tissue. Abbreviations for genes are as follows. Dhcr7: 7-dehydrocholesterol reductase; Fdft1: farnesyl-diphosphate farnesyltransferase 1; Sc4mol: sterol-C4-methyl oxidase-like; Idi1: isopentenyl-diphosphate delta isomerase 1; Mvd: mevalonate (diphospho) decarboxylase; Hmgcs: 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1; Hmgcr: HMG Coenzyme A reductase; Lss: lanosterol synthase; Cyp51: cytochrome P450 family 51; Sqle: Squalene Epoxidase. A red line between Control and Lactating symbols for a given gene indicates p > .0.01 for the tissue pairwise comparison within the tissue from the mixed models repeated measures ANOVA on the log2 transformed intensities; the change was not considered significant for the purposes of determining a list of differentially expressed genes. A black line between C and L symbols indicates p < 0.01 as described above.

Back to article page

BMC Genomics

ISSN: 1471-2164

Contact us