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Table 1 Comparison of methylated and unmethylated promoter CGIs.

From: Correlating CpG islands, motifs, and sequence variants in human chromosome 21

 

Unmethylated CpG Islands

Methylated CpG Islands

P-Value

Number of Islands

150

13

 

Length

1188.27±161.48

1145.92±359.79

< 1.48 x 10-11

GC Content (%)

60.76±10.34

66.44±19.34

< 1.81 x 10-2

Obs CpG /Exp CpG

1.49±0.25

1.63±0.47

< 1.81 x 10-2

  1. Methylated and unmethylated promoter CGIs were compared by sequence for average length, GC content (%), and ObsCpG/ExpCpG ratio. P-values were determine using the Kolmogorov-Smirnov two-sample test.