Comparative analysis and assessment of M. tuberculosis H37Rv protein-protein interaction datasets

BMC Genomics

Table 5 Comparison of physical interactions and predicted physical interologs datasets

Organism	Benchmark dataset	Testing PPI dataset	Jaccard coefficient	Precision	Recall	Overlapping PPIs No.
M. tuberculosis H37Rv	H37Rv pull-down interologs	H37Rv physical interologs	0.021	0.205	0.023	40
M. tuberculosis H37Rv	H37Rv B2H PPI	H37Rv physical interologs	0.005	0.005	0.050	2
S. aureus MRSA252	MRSA252 Pull Down PPI dataset	MRSA252 physical interologs	0.019	0.126	0.022	23

Summary of the comparison results between physical interactions and predicted interologs datasets. “H37Rv physical interologs dataset” consists of interologs transferred from “selected IntAct prokaryotic physical interactions dataset” to M. tuberculosis H37Rv; “MRSA252 physical interologs dataset” consists of interologs transferred from “selected IntAct prokaryotic physical interactions dataset” to S. aureus MRSA252; “H37Rv pull-down interologs dataset” consists of interologs transferred from “S. aureus MRSA252 high-throughput pull-down PPI dataset” to M. tuberculosis H37Rv.

ISSN: 1471-2164