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Table 6 Percentage of PPIs in representative two-hybrid PPI datasets having coherent informative GO terms

From: Comparative analysis and assessment of M. tuberculosis H37Rv protein-protein interaction datasets

  CC BP MF GO
S. cerevisiae Y2H PPI 49.74% 38.43% 35.90% 40.58%
S. cerevisiae random PPI 5.03% 3.70% 7.72% 7.08%
Info GO ratio of S. cerevisiae (Y2H PPI/ random) 9.88 10.38 4.65 5.73
Info GO term No. 57 173 78 365
C. jejuni Y2H PPI 47.37% 17.01% 16.27% 17.91%
C. jejuni random PPI 35.61% 11.04% 12.91% 13.97%
Info GO ratio of C. jejuni (Y2H PPI / random) 1.33 1.54 1.26 1.28
Info GO term No. 3 26 22 51
Synechocystis Y2H PPI 80.77% 26.16% 25.30% 29.47%
Synechocystis random PPI 44.94% 6.89% 8.59% 9.73%
Info GO ratio of Synechocystis (Y2H PPI / random) 1.80 3.79 2.95 3.03
Info GO term No. 3 30 30 63
M. tuberculosis B2H PPI 38.46% 14.36% 9.57% 13.83%
M. tuberculosis random PPI 38.30% 11.35% 8.35% 11.51%
Info GO ratio of M. tuberculosis (B2H PPI / random) 1.00 1.26 1.15 1.20
Info GO term No. 3 32 32 67
  1. The table is a summary of the percentage of PPIs having coherent informative GO terms, number of informative GO terms and “Info GO ratio” in each of the representative two-hybrid PPI datasets in four organisms.
  2. Info GO ratio = percentage of PPIs in two-hybrid PPI dataset having coherent informative GO terms / percentage of PPIs in random PPI dataset having coherent informative GO terms.