Comparison of HCC data coverage between Liverome and four other signature databases. For each of the databases, the number of collected HCC-related articles from which gene signatures were extracted is indicated. The four other databases show minimal overlaps with each other. Liverome’s collection is more than three times larger than any other database. One third of its data (thirty articles) is unique to Liverome. Only the articles that met our collection criteria were counted, as described in the “Construction and content” section.