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Table 1 Spearman's rank correlation coefficients (ρs) and partial correlations between gene's promoter methylation level and the number of microRNA target sites

From: Functional complementation between transcriptional methylation regulation and post-transcriptional microRNA regulation in the human genome

  Number of microRNA target sites by mirTarget2 (Nt) Number of microRNA target sites by PicTar (Np) 3' UTR length (UL)
Promoter methylation level ( m ) Correlation ρs ( m, Nt ) Partial correlation ρs ( m,Nt|gene expression level) Correlation ρs ( m, Np ) Partial correlation ρs ( m,Np|gene expression level) Correlation ρs ( m, UL ) Partial correlation ρs ( m,UL|gene expression level)
Promoter mCG/CG
(H1)
-0.29*** -0.19*** -0.29*** -0.22*** -0.31*** -0.22***
Promoter mCG/CG (IMR90) -0.26*** -0.19*** -0.28*** -0.19*** -0.29*** -0.20***
Promoter CpGO/E 0.29*** 0.16 *** 0.28*** 0.18 *** 0.31*** 0.19 ***
  1. A germline tissue (FETAL.OVARY.14.4WK) having the most significant correlation between expression level and promoter region CpG O/E ratio was selected [30].*** P< 10-15.