Table 1 Spearman's rank correlation coefficients (ρs) and partial correlations between gene's promoter methylation level and the number of microRNA target sites
Number of microRNA target sites by mirTarget2 (Nt) | Number of microRNA target sites by PicTar (Np) | 3' UTR length (UL) | ||||
|---|---|---|---|---|---|---|
Promoter methylation level ( m ) | Correlation ρs ( m, Nt ) | Partial correlation ρs ( m,Nt|gene expression level) | Correlation ρs ( m, Np ) | Partial correlation ρs ( m,Np|gene expression level) | Correlation ρs ( m, UL ) | Partial correlation ρs ( m,UL|gene expression level) |
Promoter mCG/CG (H1) | -0.29*** | -0.19*** | -0.29*** | -0.22*** | -0.31*** | -0.22*** |
Promoter mCG/CG (IMR90) | -0.26*** | -0.19*** | -0.28*** | -0.19*** | -0.29*** | -0.20*** |
Promoter CpGO/E | 0.29*** | 0.16 ***† | 0.28*** | 0.18 ***† | 0.31*** | 0.19 ***† |