Structural organization of the newly identified actinomycete integrative and conjugative element (AICE) pACPL from Actinoplanes sp. SE50/110 in comparison with other AICEs from closely related species. (A) pACPL (13.6 kb), the first AICE found in the Actinoplanes genus from Actinoplanes sp. SE50/110; (B) pSAM2 (10.9 kb) from Streptomyces ambofaciens; (C) pMR2 (11.2 kb) from Micromonospora rosaria SCC2095; (D) SLP1 (17.3 kb) from Streptomyces coelicolor A3(2); (E, F) AICESare 1562 (13.3 kb) and AICESare 1922 (14.4 kb) from Salinispora arenicola CNS-205; (G) AICEStrop 0058 (14.9 kb) from Salinispora tropica CNB-440. B-G adapted from .