Functional organization and its implication in evolution of the human protein-protein interaction network

BMC Genomics

Table 5 Changes in the correlation coefficients before and after functions are controlled for

	Interaction Degree		Clustering Coefficient		Network Distance
	Spearman correlation coefficient	Test statistics	Spearman correlation coefficient	Test statistics	Spearman correlation coefficient	Test statistics
Intact	-0.212		-0.110		0.224
Controlling Biological Process	-0.172	t = 1.98 df = 29 p = 0.058	-0.004	t = 2.95 df = 29 p = 0.006	0.191	t = -1.21 df = 29 p = 0.234
Controlling Molecular Function	-0.191	t = 1.06 df = 26 p = 0.299	-0.060	t = 2.29 df = 26 p = 0.031	0.209	t = -0.71 df = 26 p = 0.484

The Spearman correlation coefficient represents the tendency of network topologies to change along with temporal groups

ISSN: 1471-2164