Genome-wide recruitment to Polycomb-modified chromatin and activity regulation of the synovial sarcoma oncogene SYT-SSX2

Table 5 Distribution of SYT-SSX2-overlapping epigenetic markers relative to transcription start sites of upregulated genes

Marker	In	0-5	5-10	10-15	15-20	20-25	25-30	30-35	35-40	40-45	45-50
DNA me	9.55	4.46	0.32	0.96	0.32	0	0	0.64	0.32	0.64	0.64
H3K4me1	18.8	5.10	2.23	5.41	5.73	2.55	6.37	3.82	4.46	4.46	5.73
H3K4me2	8.28	5.10	0.32	1.27	0.64	0.64	0.96	0.32	0.96	0.96	0.64
H3K4me3	8.60	4.14	0.64	1.27	0.32	0.64	0.64	0.32	0.64	1.27	0.96
H3K27me3	50.0	31.2	29.3	25.7	23.9	24.5	23.6	21.3	21.3	22.0	19.4
H3K9Ac	5.10	0.64	0.32	0.64	0	0.32	0.96	0.32	0.64	1.91	0.64
H3K18Ac	9.24	2.23	1.91	2.23	2.55	2.55	2.55	2.23	3.82	4.78	3.50
H3K36me3	2.87	0	0	0.32	0.64	0.32	0.32	0.96	0	0.96	0.32
H4K12Ac	7.32	1.27	0.64	1.59	1.27	0.96	0.64	1.27	1.59	1.91	0.96
H2BUb	1.27	0	0	0.32	0.32	0.64	0.32	0.64	0	0.32	0
PolII	10.2	3.18	1.59	1.91	1.27	1.27	1.27	1.59	1.27	2.23	2.55

Percentages are relative to the total number of upregulated genes with SYT-SSX2 peaks that overlap any epigenetic marker from 0-50kb upstream of the TSS and including the gene body (total = 314). Numbers in first row represent distances measured in kilobases.

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