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Figure 5 | BMC Genomics

Figure 5

From: The immune gene repertoire of an important viral reservoir, the Australian black flying fox

Figure 5

a. Alignment of deduced amino acid sequences of bat NKG2 with human and mouse NKG2A and NKG2C. Sequences are divided into cytoplasmic, transmembrane, stalk, and lectin domains. The predicted ITIM motifs in the cytoplasmic domain are shaded. The conserved cysteine residue in the stalk predicted to be involved in interchain disulphide bond formation with CD94 is shaded and indicated with an asterisk. Dashes indicate similarity and dots indicate gaps. b. Alignment of the deduced amino acid sequences of bat CD94 with the human and mouse orthologues. Sequences are divided into cytoplasmic, transmembrane, stalk, and lectin domains. Conserved cysteines predicted to be involved in disulphide bond formation are shaded. Cysteine pairs are indicated by identical numbers below the cysteine. The cysteine predicted to form a disulphide bond with NKG2 is indicated with an asterisk.

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