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Table 6 AIV viral targets of differentially expressed miRNAs between lungs of infected and non-infected chicken (P < 0.05, Q < 0.05 and Ratio > 2)

From: Integrated analysis of microRNA expression and mRNA transcriptome in lungs of avian influenza virus infected broilers

miRNA

Ratio of Infected/Non-infected (Normalized)

AIV RNA segments

gga-miR-153

Specifically expressed in infected lung

HA, NA, PA, PB1 and PB2

gga-miR-34a

Specifically expressed in infected lung

HA, NA, PA, PB1 and PB2

gga-miR-202

+9.93

HA, M, NA, NP, NS, PA, PB1 and PB2

gga-miR-32

+7.98

HA and NS

gga-miR-211

+7.45

HA, M, NA, NP, NS, PA, PB1 and PB2

gga-miR-19b

+6.55

HA, NS, PA and PB1

gga-miR-18a

+4.75

HA, M, NA, PB1 and PB2

gga-miR-18b

+3.62

HA, M, NA, PB1 and PB2

gga-miR-155

+3.55

HA, NA, NP, NS and PB1

gga-miR-15a

+3.48

HA, M NP, NS and PB2

gga-miR-223

+3.19

HA, NA, PB1 and PB2

gga-miR-30b

+3.06

M and NA

gga-miR-142-3p

+2.84

HA, NA, PA, PB1 and PB2

gga-miR-106

+2.83

HA, NA, PA, PB1 and PB2

gga-miR-20a

+2.78

HA, NA, NP, PB1 and PB2

gga-miR-146a

+2.59

HA, M, NA, NP, NS, PA, PB1 and PB2

gga-miR-20b

+2.41

HA, M, NA, NP, NS, PB1 and PB2

gga-miR-29a

+2.36

HA, M, NA, NP, PA, PB1 and PB2

gga-miR-29c

+2.36

HA, M, NA, NP, PA and PB1

gga-miR-24

+2.34

HA, M, NA, NP, NS, PA, PB1 and PB2

gga-miR-7b

+2.33

HA, M, NA, PA, PB1

gga-miR-17-5p

+2.32

HA, M, NA, NP, PA, PB1 and PB2

gga-miR-23b

+2.25

HA, M, PA and PB1

gga-miR-17-3p

+2.15

HA, M, NA, NP, PA and PB2

gga-miR-92

+2.07

HA, M, NP, NS, PB2

gga-miR-206

−2.86

HA, NA, NP, PB1 and PB2

gga-miR-301

−3.03

HA, NA, PB1 and PB2

gga-miR-187

−4.35

NA, NP, PB1 and PB2

  1. Note: + Up-regulated with AIV infection; - Down-regulated with AIV infection.