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Table 7 Differentially expressed immune related host mRNAs between lungs of infected and non-infected chickens (P < 0.05 and Fold-change > 1.5)

From: Integrated analysis of microRNA expression and mRNA transcriptome in lungs of avian influenza virus infected broilers

Gene description

Gene Accession

Infected vs. Non-infected (Fold-change)

miRNA1(fold change)

MX1 myxovirus (influenza virus) resistance 1[27]

Z23168

+11.46

gga-miR-155(+3.55)

gga-miR-206(−2.86)

Interleukin 8 (IL8)[28]

M16199

+11.03

gga-miR-32(+7.98)

Interferon regulatory factor 7 (IRF7)[29]

U20338

+2.11

gga-miR-142-5p(+2.84)

Interleukin1receptor-like1, transcript variant1[51]

AB041738

+1.65

gga-miR-460 (only expressed in infected lungs)

TNF receptor superfamily, member 19[30]

BX931334

−1.85

gga-miR-187(−4.35)

Tipartite motif-containing 7.1[52]

BX934475

−1.81

NA2

RAC serine/threonine-protein kinase3 (ATK3)[53]

BX950472

−1.65

NA

C-fringe 1[54]

U97157

−1.52

NA

  1. Note: 1miRNAs targeting on differentially expressed immune related genes; 2 No miRNAs targeting on the gene; +: Up-regulated with AIV infection; –: Down- regulated with AIV infection.