Table 1 Genes significantly regulated upon TSA and BMP2 treatment
Gene name | Gene name symbol | BMP2 | TSA | ||
|---|---|---|---|---|---|
6 h | 24 h | 6 h | 24 h | ||
G protein-coupled receptor 17 | Gpr17 | −3.13 | −30.90 | −6.80 | −80.21 |
ectonucleotide pyrophosphatase/phosphodiesterase 6 | Enpp6 | −1.99 | −23.08 | −3.93 | −30.02 |
LIM and senescent cell antigen like domains 2 | Lims2 | −2.80 | −24.72 | −4.61 | −27.27 |
plexin B3 | Plxnb3 | −1.12 | −8.69 | −4.61 | −26.64 |
serine/arginine-rich protein specific kinase 3 | Srpk3 | −1.22 | −7.54 | −6.01 | −26.60 |
galactose-3-O-sulfotransferase 1 | Gal3st1 | −1.01 | −8.92 | −4.96 | −18.20 |
breast carcinoma amplified sequence 1 | Bcas1 | −2.80 | −24.38 | −9.53 | −17.36 |
bone morphogenetic protein 4 | Bmp4 | −9.01 | −34.17 | −3.25 | −15.47 |
S100 protein. beta polypeptide. neural | S100b | 1.19 | −4.14 | −3.54 | −14.71 |
ELOVL family member 7. elongation of long chain fatty acids | Elovl7 | −1.21 | −6.57 | −3.33 | −14.34 |
breast carcinoma amplified sequence 1 | Bcas1 | −1.55 | −11.02 | −2.93 | −13.89 |
RAB33A. member of RAS oncogene family | Rab33a | −1.50 | −9.41 | −7.10 | −13.66 |
SRY-box containing gene 10 | Sox10 | −1.28 | −6.73 | −2.81 | −13.51 |
protein kinase C. theta | Prkcq | −2.52 | −4.70 | −11.82 | −12.45 |
tubulin. beta 4 | Tubb4 | −1.68 | −5.93 | −4.74 | −12.31 |
Down syndrome cell adhesion molecule | Dscam | −2.02 | −4.85 | −3.70 | −11.67 |
oligodendrocyte myelin glycoprotein | Omg | −1.38 | −2.61 | −11.48 | −9.86 |
four and a half LIM domains 2 | Fhl2 | −1.11 | −11.15 | −6.79 | −9.48 |
glycerol-3-phosphate dehydrogenase 1 | Gpd1 | −2.93 | −8.02 | −2.50 | −7.87 |
chimerin (chimaerin) 2 | Chn2 | −1.41 | −6.46 | −5.09 | −7.68 |
protein tyrosine phosphatase. receptor type. E | Ptpre | −18.37 | −16.45 | −2.53 | −7.19 |
Down syndrome cell adhesion molecule-like 1 | Dscaml1 | −3.25 | −2.48 | −3.19 | −5.91 |
phosphatase and actin regulator 3 | Phactr3 | −3.18 | −6.73 | −1.86 | −5.81 |
MAD homolog 7 (Drosophila) | Smad7 | 4.51 | 6.86 | −3.24 | −5.69 |
family with sequence similarity 19. member A2 | Fam19a2 | 3.13 | 1.03 | −3.10 | −5.38 |
leucine rich repeat transmembrane neuronal 1 | Lrrtm1 | −1.90 | −4.49 | −7.54 | −5.20 |
solute carrier family 24 member 3 | Slc24a3 | −2.44 | −1.87 | −3.79 | −4.96 |
delta-like 3 (Drosophila) | Dll3 | −4.14 | −3.64 | −3.32 | −4.49 |
shroom family member 2 | Shroom2 | −1.39 | −2.78 | −3.69 | −4.46 |
WAS/WASL interacting protein family member 1 | Wipf1 | −1.20 | −2.68 | −3.89 | −4.20 |
actin filament associated protein 1-like 2 | Afap1l2 | −3.47 | −3.68 | −4.84 | −4.16 |
seizure related 6 homolog like | Sez6l | −3.30 | −2.91 | −2.92 | −4.16 |
proline rich region 18 | Prr18 | −1.71 | −3.35 | −6.74 | −4.09 |
striatin. calmodulin binding protein | Strn | −1.55 | −2.35 | −2.94 | −4.07 |
G0/G1 switch gene 2 | G0s2 | −3.89 | −5.35 | −6.74 | −4.02 |
cytoplasmic FMR1 interacting protein 2 | Cyfip2 | −2.12 | −4.22 | −2.53 | −3.79 |
platelet derived growth factor alpha | Pdgfa | −2.27 | −5.57 | −4.54 | −3.59 |
3'-phosphoadenosine 5'-phosphosulfate synthase 2 | Papss2 | 6.90 | 10.70 | −2.50 | −3.34 |
dedicator of cytokinesis 9 | Dock9 | −1.86 | −5.59 | −2.63 | −3.28 |
zinc finger protein 365 | Zfp365 | −3.75 | −5.30 | −2.43 | −3.23 |
ring finger protein 122 | Rnf122 | −2.05 | −2.76 | −2.63 | −2.92 |
SH3-domain binding protein 4 | Sh3bp4 | −3.26 | −4.35 | −1.82 | −2.79 |
erythrocyte protein band 4.1 | Epb4.1 | −2.43 | −3.67 | −1.30 | −2.55 |
TNF receptor associated factor 4 | Traf4 | −3.54 | −4.89 | −2.20 | −2.45 |
myelocytomatosis oncogene | Myc | −2.37 | −4.17 | −3.82 | −1.70 |
Ca2 + −dependent secretion activator | Cadps | 2.90 | 4.96 | −2.52 | −1.39 |
GS homeobox 1 | Gsx1 | −2.52 | −5.17 | −4.86 | −1.20 |
leucine rich repeat and fibronectin type III. extracellular 1 | Elfn1 | −4.08 | −6.57 | −2.81 | −1.06 |
myosin regulatory light chain interacting protein | Mylip | 7.66 | 4.10 | 3.47 | 1.55 |
tumor necrosis factor receptor superfamily. member 12a | Tnfrsf12a | 9.04 | 10.10 | 7.39 | 1.87 |
carbonic anhydrase 8 | Car8 | −2.65 | −6.46 | 2.65 | 2.06 |
epidermal growth factor receptor | Egfr | −4.15 | −7.93 | −1.95 | 2.73 |
BMP and activin membrane-bound inhibitor. homolog (Xenopus laevis) | Bambi | 3.46 | 3.60 | 2.61 | 3.41 |
follistatin | Fst | 16.56 | 19.63 | 1.55 | 4.18 |
Rho GTPase activating protein 29 | Arhgap29 | 2.69 | 8.01 | 5.84 | 4.35 |
DIRAS family. GTP-binding RAS-like 2 | Diras2 | 12.12 | 99.94 | 1.09 | 4.51 |
aquaporin 11 | Aqp11 | 1.66 | 5.08 | 3.24 | 4.61 |
Kruppel-like factor 4 (gut) | Klf4 | 5.39 | 13.51 | 7.94 | 4.74 |
regulator of G-protein signalling 10 | Rgs10 | 1.01 | 3.25 | 3.20 | 6.39 |
EF hand domain containing 1 | Efhd1 | −1.52 | −5.45 | 3.22 | 6.77 |
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention eceptor 3 | Kdelr3 | 1.62 | 7.32 | 11.15 | 6.87 |
zinc finger. CCHC domain containing 12 | Zcchc12 | 1.95 | 4.24 | 8.50 | 9.35 |
family with sequence similarity 70. member A | Fam70a | 7.28 | 13.35 | 2.99 | 16.08 |
predicted gene 98 | Gm98 | −2.39 | −13.78 | −4.13 | −20.43 |