Heat map of dN/dS values for Cat compared to Dog, Mouse and Human. A set of 711 cDNA sequences with orthologs in dog, mouse and human were sorted by dN/dS (w) value to generate three groups corresponding to the top 25%, bottom 25% and middle 50%. Each list was used to query the GeneGO database for metabolic pathways. A non-random pattern was observed with genes with higher dN/dS (w) more frequently associated with metabolic pathways. Red indicates higher dN/dS (w) and blue corresponds to lower dN/dS (w) value.