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Table 6 Conserved and Divergent Metabolic Pathways

From: Sequencing and comparative genomic analysis of 1227 Felis catus cDNA sequences enriched for developmental, clinical and nutritional phenotypes

Most conserved

p-value

Most divergent

p-value

1-icosatrienoyl-sn-glycero-3-phosphocholine pathway

6.01E-03

(L)-leucine pathways and transport

2.42E-03

1-docosahexaenoyl-glycerol_3-phosphocholine pathway

6.96E-03

GalNAcbeta1-3Gal pathway

3.06E-03

2-arachidonoyl-glycerol_3-phosphocholine pathway

8.16E-03

Branched-chain amino acid metabolism

4.08E-03

Phosphatidylinositol-3,4,5-triphosphate pathway

1.61E-02

Estrone and Estradiol metabolism

2.23E-02

[O-hexadecanoyl-(L)-carnitine pathway

2.10E-02

N-acyl-sphingosine phosphate pathway

2.48E-02

Phosphatidylinositol-4,5-diphosphate pathway

3.18E-02

HETE, HPETE and Leukotriene4 metabolism

6.47E-02

Glutamic acid pathway

3.83E-02

Tryptophan, Phenylalanine, Methionine metabolism

7.02E-02

L-glutamate pathways and transport

5.94E-02

Tryptophan, Phenylalanine, Tyramine, Methionine metabolism and transport

8.30E-02

Glycolysis, Glucogenesis and glucose transport

6.26E-02

Lyso-Phosphatidylserine pathway

8.88E-02

Glutamic acid pathways and transport

6.83E-02

Cholesterol biosynthesis

1.13E-01

  1. The ten most highly conserved, and the ten most highly divergent metabolic pathways are listed along with the p-value for each pathway. The most conserved pathways are associated with the lowest dN/dS values, whereas the most divergent pathways are associated with the highest dN/dS values.