A microRNA activity map of human mesenchymal tumors: connections to oncogenic pathways; an integrative transcriptomic study

Table 2 Histology-specific miRNA deregulation patterns

LEIO	LIPOm	FIBRO	SYN
hsa-miR-128b
*hsa-miR-100*
*hsa-miR-99a*	hsa-miR-17-3p¹	hsa-miR-107¹	-	Activated
*hsa-miR-212*		hsa-miR-128a		miRNAs
hsa-miR-199b
hsa-miR-98¹
			hsa-miR-217¹
			hsa-miR-181a
			hsa-miR-330
		hsa-miR-30a-3p	hsa-miR-29c
hsa-miR-374	hsa-miR-302a*	hsa-miR-154*	hsa-miR-221	Silenced miRNAs
hsa-miR-361	hsa-miR-130	hsa-miR-21¹	hsa-miR-217¹
		hsa-miR-208	hsa-miR-424
			hsa-miR-25
			hsa-miR-126*
			hsa-miR-31
			hsa-miR-302a
			hsa-miR-26a¹
OSTEOSARCOMA SPECIFIC miRNAs
*hsa-miR-122a*	hsa-miR-7 g
hsa-miR-18	*hsa-miR-147*
*hsa-miR-34c*	*hsa-miR-210*	Activated mIRNAs
hsa-miR-375	*hsa-miR-187*
*hsa-miR-204*	*hsa-miR-134*
*hsa-miR-138*	*hsa-miR-211*

Boldface denotes activated or silenced miRNAs compared to mesenchymal normal tissue only. Boldface italicized text denotes activated or silenced miRNAs compared to both mesenchymal normal tissue and all normal tissue. A superscript 1 denotes miRNAs which are also differentially activated in epithelial cancers.

ISSN: 1471-2164