Table 1 Annotation clusters of genes affected by lead
Annotation Cluster 1 | Enrichment Score: 9.7 | Â | Â | Â |
|---|---|---|---|---|
Category | Term | Count | P-value | FDR |
UP_SEQ_FEATURE | metal ion-binding site: Divalent metal cation; cluster B | 7 | 2.02E-10 | 3.01E-07 |
UP_SEQ_FEATURE | metal ion-binding site: Divalent metal cation; cluster A | 7 | 2.02E-10 | 3.01E-07 |
PIR_SUPERFAMILY | PIRSF002564:metallothionein | 7 | 2.15E-10 | 2.26E-07 |
INTERPRO | IPR018064: Metallothionein, vertebrate, metal binding site | 7 | 2.23E-10 | 3.05E-07 |
SP_PIR_KEYWORDS | metal-thiolate cluster | 7 | 3.86E-10 | 4.98E-07 |
INTERPRO | IPR000006: Metallothionein, vertebrate | 7 | 4.43E-10 | 6.06E-07 |
INTERPRO | IPR003019: Metallothionein superfamily, eukaryotic | 7 | 4.43E-10 | 6.06E-07 |
Annotation Cluster 2 | Enrichment Score: 5.8 | Â | Â | Â |
Category | Term | Count | P-value | FDR |
SP_PIR_KEYWORDS | cadmium | 6 | 2.79E-09 | 3.59E-06 |
GOTERM_MF_FAT | GO:0046870 ~ cadmium ion binding | 6 | 2.94E-08 | 4.01E-05 |
SP_PIR_KEYWORDS | copper | 6 | 1.47E-04 | 0.19 |
GOTERM_MF_FAT | GO:0005507 ~ copper ion binding | 6 | 7.95E-04 | 1.08 |