Skip to main content

Table 1 Annotation clusters of genes affected by lead

From: Analysis of lead toxicity in human cells

Annotation Cluster 1 Enrichment Score: 9.7    
Category Term Count P-value FDR
UP_SEQ_FEATURE metal ion-binding site: Divalent metal cation; cluster B 7 2.02E-10 3.01E-07
UP_SEQ_FEATURE metal ion-binding site: Divalent metal cation; cluster A 7 2.02E-10 3.01E-07
PIR_SUPERFAMILY PIRSF002564:metallothionein 7 2.15E-10 2.26E-07
INTERPRO IPR018064: Metallothionein, vertebrate, metal binding site 7 2.23E-10 3.05E-07
SP_PIR_KEYWORDS metal-thiolate cluster 7 3.86E-10 4.98E-07
INTERPRO IPR000006: Metallothionein, vertebrate 7 4.43E-10 6.06E-07
INTERPRO IPR003019: Metallothionein superfamily, eukaryotic 7 4.43E-10 6.06E-07
Annotation Cluster 2 Enrichment Score: 5.8    
Category Term Count P-value FDR
SP_PIR_KEYWORDS cadmium 6 2.79E-09 3.59E-06
GOTERM_MF_FAT GO:0046870 ~ cadmium ion binding 6 2.94E-08 4.01E-05
SP_PIR_KEYWORDS copper 6 1.47E-04 0.19
GOTERM_MF_FAT GO:0005507 ~ copper ion binding 6 7.95E-04 1.08