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Table 1 Numbers of genes (with known or predicted functions) that exhibited significant up- or down-regulation after inactivation of ccpA

From: Pleiotropic functions of catabolite control protein CcpA in Butanol-producing Clostridium acetobutylicum

Function category No. of genes affected by ccpA inactivation
  M (Middle exponential phase) L (Late exponential phase) T (Transition phase) S (Stationary phase)
  Up-regulation Down-regulation Up-regulation Down-regulation Up-regulation Down-regulation Up-regulation Down-regulation
G. Carbohydrate transport and metabolism 96 9 96 10 84 10 103 9
E. Amino acid transport and metabolism 38 28 9 38 31 52 42 18
H. Coenzyme transport and metabolism 21 12 10 11 16 9 22 22
R. General function prediction only 20 19 20 24 24 23 24 36
K. Transcription 19 13 20 13 22 13 25 22
F. Nucleotide transport and metabolism 14 4 14 1 13 3 11 7
T. Signal transduction mechanisms 11 15 12 7 11 19 19 10
C. Energy production and conversion 10 22 5 15 9 11 16 12
I. Lipid transport and metabolism 9 3 9 3 9 2 11 14
O. Posttranslational modification, protein turnover, chaperones 9 10 2 17 5 16 7 8
N. Cell mobility 8 12 11 4 7 12 14 3
M. Cell wall/membrane biogenesis 8 16 10 10 9 20 13 35
P. Inorganic ion transport and metabolism 8 22 5 25 11 17 25 18
J. Translation 6 5 10 3 5 3 6 38
L. Replication, recombination and repair 5 2 9 1 3 0 4 12
Q. Secondary metabolites biosynthesis, transport and catabolism 4 1 3 1 3 1 3 6
V. Defense mechanisms 2 3 2 1 4 2 5 7
D. Cell cycle control, mitosis and meiosis 1 1 2 1 1 1 2 4
U. Intracellular trafficking and secretion 1 0 1 0 2 0 4 4
S. Function unknown 11 22 12 21 13 20 18 37
Not in COGs 93 57 115 46 75 50 124 149
Total 370 266 352 244 330 278 465 471