Growth profiles of one of the triplicate A. niger HacAWT(A) and HacA CA(B) batch cultures. Dry weight biomass concentration (gDWkg-1) as a function of time (h) illustrates the growth of the cultures. The maximum specific growth rate for each culture was determined from the slope (α) of the ln transformation of biomass (Cbiomass) in the exponential growth phase as a function of time (h), as well from log transformation of alkali addition as a function of time (h). Dash-line represents the end of the exponential growth phase (depletion of glucose). Arrows indicate time-points where mycelium was harvested for transcriptomic analysis.