Figure 1

Hematoxylin-eosin-stained paraffin sections of control and inflamed ileum. a: The control ileum showed no pathological signs of inflammatory activity b: The S. mansoni-infected ileum was characterized by the presence of granulomas with entrapped parasite eggs (asterisk), thickening of the tunica muscularis and broadening of the villi c: The TNBS-treated ileum showed ablated and broken villi, signs of regeneration of the mucosal epithelium (arrows), subepithelial cysts and a high number of immune cells in the lamina propria as well as in the vicinity of enteric ganglia. Scale bar = 200 μm.