Skip to main content

Table 2 Associations between expression levels of key miRNA biogenesis genes and mean RE-score

From: The regulatory effect of miRNAs is a heritable genetic trait in humans

 

CEU

YRI

Pooled

 

Bonferroni P

Slope

Bonferroni P

Slope

Bonferroni P

Slope

DROSHA

9.42 × 10−03

-10.23

1.37 × 10−05

-22.12

5.19 × 10−06

-15.64

DGCR8

0.036

11.57

0.95

-0.46

0.37

6.23

XPO5

0.47

-3.03

1.38 × 10−04

-17.85

2.17 × 10−03

-10.74

RAN

0.27

0.49

0.14

-0.94

0.75

-0.12

DICER1

8.51 × 10−03

-13.77

1.97 × 10−09

-26.18

5.57 × 10−10

-21.72

TRBP

2.95 × 10−05

12.26

0.085

8.12

2.68 × 10−04

10.60

EIF2C2

0.022

-6.25

1.39 × 10−07

-9.07

1.88 × 10−08

-8.41

  1. P-values and slopes from the linear regression of expression level of genes in the miRNA biogenesis pathway against mean RE-score, in the CEU, YRI and for both populations pooled.