Synteny mapping of speG regions in SDSE and GAS genomes. (A) Genome context of speG and the 50 kb surrounding regions of the GGS_124 and 13 GAS strains. Each position (bp) on each genome is shown in Additional file10. Some sequences encoding small peptides (20 to 30 amino acid residues) were annotated as having unknown functions or as hypothetical proteins and were omitted from this figure, because their assignments depended on the annotator. Transposase and IS elements are shown in red. hyp (in grey) indicates sequences encoding ‘hypothetical proteins’. Genes of the speG region of GGS_124 were inversely aligned. Pseudogenes are marked with asterisks. (B) Genome context of speG or the corresponding region in speG(+) and speG(−) SDSE strains. All information on the strains used in this study is shown in Additional file1.