Comparison of arsenic resistance loci of F. philomiragia strain ATCC 25017 (A and C) and Francisella spp. strain TX07-7308 (B and D). The relevant ORFs marked in A and C are: Fphi_1740, transposase X; Fphi_1741 and 1750, integrase catalytic subunit; Fphi_1742, transposase; Fphi_1743, transposase; Fphi_1744, invertase/recombinase-like protein; Fphi_1745, truncated ArsB arsenite/antimonite exporter; Fphi_1746, arsenate reductase; Fphi_1747, sulfate transporter; Fphi_1748, hypothetical protein; Fphi_1749, mechanosensitive ion channel family protein; Fphi_1817, ArsR family transcriptional regulator; Fphi_1818, ArsB arsenite/antimonite exporter. The relevant ORFs marked in B and D are: F7308_0309, ArsR family transcriptional regulator; F7308_0310, Arsenical-resistance protein ACR3; F7308_1298, Arsenical-resistance protein ACR3; F7308_1299, ArsR family transcriptional regulator. t1, t2, and t3 are tRNA genes. The numbers on either side of the maps refer to the nucleotide positions in the respective chromosomes.