Table 4 Unique effects of insulin neutralization on differential gene expression
Up-regulated genes | Â | Down-regulated genes | Â | ||
|---|---|---|---|---|---|
Gene symbol | Gene title | Fold change | Gene symbol | Gene title | Fold change |
GCG | Glucagon | 2.91 | LOC425670 | glucagon receptor precursor | 2.77 |
TCP11L2 | t-complex 11 (mouse)-like 2 | 2.08 | BAK1 | BCL2-antagonist/killer 1 | 1.83 |
LOC416916 | hypothetical LOC416916 | 1.98 | CCT3 | chaperonin containing TCP1, subunit 3 (gamma) | 1.62 |
MAGI1 | membrane associated guanylate kinase, WW and PDZ domain containing 1 | 1.84 | SETD7 | SET domain containing (lysine methyltransferase) 7 | 1.62 |
SEPT10 | septin 10 | 1.79 | ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | 1.62 |
LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae); similar to LSM14 homolog A (SCD6, S. cerevisiae) | 1.71 | AHSA1 | AHA1, activator of heat shock 90 kDa protein ATPase homolog 1 (yeast) | 1.62 |
| Â | Â | Â | TOE1 | target of EGR1, member 1 (nuclear) | 1.59 |
| Â | Â | Â | AZIN1 | antizyme inhibitor 1 | 1.56 |